The JRC applied six measurement techniques to standardise the activity of an 241Am solution in the frame of the 2003 key comparison CCRI(II)-K2.Am-241. The methods used were alpha-particle counting at a defined small solid angle, high-efficiency particle and photon counting with a windowless 4π CsI(Tl) sandwich spectrometer, 4π alpha counting with a pressurised proportional counter, alpha-gamma coincidence counting and sum counting with a small pressurised proportional counter and a NaI(Tl) well detector, and 4π counting with a liquid scintillation counter. All results were consistent and an unusually low measurement uncertainty of 0.054% was achieved. An overview is presented of the outcome of the key comparison exercise, which demonstrates international equivalence.