Detection methods and strategies for improving medication compliance

Bond, William S.; Hussar, Daniel A.

doi:10.1093/ajhp/48.9.1978

Cited by 125 publications

(84 citation statements)

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“…They register date and time of every opening of the pill bottle, and are considered as the best measurement instrument currently available. 9,20,[39][40][41] The data can be downloaded from the MEMS cap with a communication device and a computer, and Powerview software (AARDEX Ltd.) presents the data in simple plots. These plots can be used to provide feedback about behavior, and to identify suboptimal adherence patterns, both essential components of the AIM strategy.…”

Section: Methodsmentioning

confidence: 99%

Theory- and Evidence-Based Intervention to Improve Adherence to Antiretroviral Therapy Among HIVInfected Patients in The Netherlands: A Pilot Study

Bruin

Hospers

Borne

et al. 2005

AIDS Patient Care and STDs

101

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The objectives of this study were to describe and pilot-test a theory- and evidence-based intervention to improve adherence of HIV-infected patients with antiretroviral medication. Twenty-six treatment-experienced patients (>6 months on treatment) participated in a within-subject comparison design. Adherence was measured electronically with Medication Event Monitoring System (MEMS) caps for at least 5 months: 2 months before the intervention and 3 months during the intervention. MEMS data were used to measure the outcome of the intervention, but also served as feedback to participants during the intervention. Mean adherence during the month before intervention was compared to mean adherence during the third month of intervention. Data for the process evaluation were gathered through direct observation and semi-structured interviews. Adherence improved significantly during the intervention (Z = -2.1, p < 0.05). Mean adherence (percentage of prescribed doses taken within correct time interval) before the intervention was 81.8% compared to 92.5% during the third month of the intervention. More than 65% of the nonadherent patients (<95% adherence) before the intervention were adherent during the third month of the intervention. Both health care professionals and patients positively evaluated the intervention protocol and the electronic measurement of adherence. The only critique from some patients was the lack of userfriendliness of the MEMS cap and its medication container (size and shape). It can be concluded that the proposed intervention fits in standard care procedures, can be executed by trained HIV nurses, seems to improve adherence to antiretroviral medication, and is positively evaluated by the users. Large-scale and long-term research is warranted.

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Section: Methodsmentioning

confidence: 99%

Theory- and Evidence-Based Intervention to Improve Adherence to Antiretroviral Therapy Among HIVInfected Patients in The Netherlands: A Pilot Study

Bruin

Hospers

Borne

et al. 2005

AIDS Patient Care and STDs

101

View full text Add to dashboard Cite

show abstract

“…the direct and indirect costs of poor adherence have been estimated to be $ 100 billion per year in the United States [4]. Estimates of adherence range from 4 to 92%, with an average of 50% adherence to long-term therapy reported to occur in developed countries [1,5,6]. Rates in developing countries have been found to be even lower than this, a finding partially attributable to the low levels of literacy in these countries [1].…”

Section: Introductionmentioning

confidence: 99%

Medicine labels incorporating pictograms: do they influence understanding and adherence?

Dowse

Ehlers

2005

Patient Education and Counseling

214

159

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“…1 The economic burden of medication nonadherence in Canada has been estimated at between $7 to $9 billion per year. 2 Potential consequences of medication nonadherence on health status include delayed recovery from acute illness, accelerated progression of chronic disease, and the resulting need for more aggressive treatments that may further increase the risk for drug-induced illness.…”

mentioning

confidence: 99%

Validity of a Prescription Claims Database to Estimate Medication Adherence in Older Persons

Grymonpre

Cheang²,

Fraser³

et al. 2006

Medical Care

157

119

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Detection methods and strategies for improving medication compliance

Cited by 125 publications

References 0 publications

Theory- and Evidence-Based Intervention to Improve Adherence to Antiretroviral Therapy Among HIVInfected Patients in The Netherlands: A Pilot Study

Theory- and Evidence-Based Intervention to Improve Adherence to Antiretroviral Therapy Among HIVInfected Patients in The Netherlands: A Pilot Study

Medicine labels incorporating pictograms: do they influence understanding and adherence?

Validity of a Prescription Claims Database to Estimate Medication Adherence in Older Persons

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