“…Other sources include livestock waste runoff (Yost et al, 2013), effluent from human wastewater (Belfroid et al, 1999;Sun et al, 2013), pulp and paper mills (Jenkins et al, 2001;Jenkins et al, 2003), and crop production in intensive agricultural areas (crops are sources of naturally-occurring phytoestrogens) (Kolpin et al, 2010). Disruption of the endocrine system by environmental EDCs is an established phenomenon in wildlife and plants (Adeel et al, 2017;Murray et al, 2017;UNEP/WHO, 2012). Evidence of adverse effects on human reproductive and thyroid systems is also growing (Annamalai and Namasivayam, 2015; UNEP/WHO, 2012), and EDCs are hypothesized risk factors for some hormone-related malignancies (Adeel et al, 2017;Street et al, 2018).…”