Detection of acute myocardial ischemic injury by gender using a novel cardiac electrical biomarker

Diagnostic value of the cardiac electrical biomarker, a novel ECG marker indicating myocardial injury, in patients with symptoms suggestive of non‐ST‐elevation myocardial infarction

“…The findings of this large diagnostic study extend and corroborate previous pilot studies on the possible clinical utility of the CEB for the diagnosis of AMI (Schreck & Fishberg, , ). In the largest published series to date, Schreck and Fishberg used 508 ECG obtained from various ECG databases and reported a sensitivity of 85%–94% and a specificity of 93% for the CEB to automatically detect standard ECG changes suggestive of myocardial ischemia (Schreck & Fishberg, ).…”

“…Multipolar activity rises from myocardial ischemic injury altered polarization behavior of affected myocardial cells. Two pilot studies showed a high diagnostic accuracy of the CEB for the detection of AMI when compared to standard ST‐segment analysis (Schreck & Fishberg, , ). A third study found an association between increased CEB values and increased high‐sensitive cardiac troponin I (hs‐cTnI) levels (Tereshchenko, Gatz, Feeny, & Korley, ).…”