2018
DOI: 10.1016/j.jim.2018.07.010
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Detection of antibody-secreting cells specific for the cytomegalovirus and herpes simplex virus surface antigens

Abstract: Infections with the herpes simplex virus (HSV) and the human cytomegalovirus (HCMV) can lead to life-threatening diseases, particularly in immunosuppressed patients. Furthermore, HSV infections at birth (herpes neonatorum) can result in a disseminated disease associated with a fatal multiorgan failure. Congenital HCMV infections can result in miscarriage, serious birth defects or developmental disabilities. Antibody-based interventions with hyperimmunoglobulins showed encouraging results in clinical studies, b… Show more

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