Detection of Ascorbic Acid Using Green Synthesized Carbon Quantum Dots

Abstract

In this work, carbon quantum dots (CQDs) were synthesized by microwave irradiation and were electropolymerized on glassy carbon electrode (GCE) to establish an electrochemical sensor for the selective detection of ascorbic acid (AA). Electrochemical behaviors of the prepared sensor were investigated by cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). Herein, two wide linear responses were obtained in ranges of 0.01-3 mM and 4-12 mM with a low detection limit of 10 μM to AA. High sensitivities (44.13 μA-1 μM-1 cm-2, 9.66 μA-1 μM-1 cm-2, respectively) corresponding to the linear ranges were also achieved. In addition, the electrochemical sensor exhibited good selectivity and robust anti-interference ability toward AA in the presence of dopamine (DA) and uric acid (UA). These results showed that this sensor can be used as a promising tool to detect AA in real complex systems.

Carbon Nanotubes, Graphene, and Carbon Dots as Electrochemical Biosensing Composites

“…Regarding selectivity, the presence of DA and UA did not show any interference with the electrochemical detection of AA on the surface of the CQDs/GCE electrode. Moreover, there were no interferences with Na + , Cl -, Mg 2+ , SO4 -, and glucose in samples at 100-fold concentration levels above that of the analyte using CA at +0.00 V [137]. An amide coupling reaction is used to functionalize the CDs.…”

An Overview of the Recent Developments in Carbon Quantum Dots—Promising Nanomaterials for Metal Ion Detection and (Bio)Molecule Sensing

“…The adrenaline concentration was also determined in real samples (injection sample of adrenaline bitartrate). Wei et al [173] performed a microwave-assisted synthesis of CQDs by using glucose as a precursor. The obtained CQDs were used for glassy carbon electrode modification with electropolymerization (20 cycles, ν = 50 mV/s, potential range from −1.0 to 2.0 V).…”

Electrochemical Sensors Based on Carbon Nanomaterial Used in Diagnosing Metabolic Disease

“…Owing to large number of carboxyl groups on the surface of CQDs, the sensitivity of this modified glassy carbon electrode was almost 10 times that of the unmodified glassy carbon electrode. In the second year, Wei et al ( 2019 ) established a new electrochemical sensor to quickly and accurately detect AA. CQDs were synthesized by the new method which was decorated to a glass carbon electrode by electrodeposition.…”