Detection of Benign Intracavitary Lesions in Postmenopausal Women with Abnormal Uterine Bleeding: A Prospective Comparative Study on Outpatient Hysteroscopy and Blind Biopsy

Angioni, Stefano; Loddo, Alessandro; Milano, Francesca; Piras, Bruno; Minerba, Luigi; Melis, Gian Benedetto

doi:10.1016/j.jmig.2007.10.014

Cited by 76 publications

(72 citation statements)

References 22 publications

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“…As described previously, hysteroscopy is superior to endometrial biopsy 60,61,67 (Class 3), D&C 60 (Class 3), and ultrasonography 84,85 (Class 3) for the identification of structural lesions of the endometrium such as endometrial polyps. Hysteroscopy has good diagnostic accuracy for structural lesions, such as polyps and leiomyomas, whether or not performed in an office setting, and good patient acceptability in either setting 24,86 (Class 1b).…”

Section: Hysteroscopy With Curettage and Directed Biopsymentioning

confidence: 99%

“…Although blind sampling, either by endometrial biopsy or D&C, is a satisfactory first-line technique for the detection of endometrial neoplasia that affects the entire endometrial surface, it is inadequate at detecting localized lesions such as endometrial polyps, which may be malignant [59][60][61] (Class 3). Indeed, a well-designed prospective study demonstrated that even D&C performed in the operating room missed endometrial polyps about half the time 60 (Class 3).…”

Section: Blind Endometrial Samplingmentioning

confidence: 99%

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Investigation of Women with Postmenopausal Uterine Bleeding: Clinical Practice Recommendations

Munro

2014

TPJ

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Section: Hysteroscopy With Curettage and Directed Biopsymentioning

confidence: 99%

Section: Blind Endometrial Samplingmentioning

confidence: 99%

Investigation of Women with Postmenopausal Uterine Bleeding: Clinical Practice Recommendations

Munro

2014

TPJ

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“…This data was supported by many studies. 2,8 It is apparent that hysteroscopy is much more sensitive than TVS in the detection of focal endometrial pathology, and the specificity of hysteroscopy is more than TVS in diagnosing various endometrial conditions (98.5 and 93.3% respectively) ( Table 5).…”

Section: Discussionmentioning

confidence: 99%

Hysteroscopy—A Mode of Screening Women with Postmenopausal Bleeding: Our Experience

Tandulwadkar¹,

Lodha²,

Agarwal³

et al. 2011

Journal of South Asian Federation of Obstetrics and Gynaecology

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Study Objective: 1. To study the etiology of postmenopausal bleeding. 2. To study the significance of hysteroscopy in evaluation of the etiopathogenic factors. Interventions: Clinical and sonographic evaluation followed by diagnostic and/or therapeutic hysteroscopy and guided biopsy. Hysteroscopic images were analyzed and compared with histopathological results. Measurements and main results:On hysteroscopy, endometrium is classified as suggestive of normal, atrophic, endometrial hyperplasia or endometrial carcinoma. Histopathological diagnosis was taken as a gold standard to determine the efficacy of hysteroscopy in diagnosing endometrial pathologies. The sensitivity and specificity of hysteroscopy in diagnosing endometrial pathologies was assessed. Conclusions:In women with postmenopausal bleeding, hysteroscopy is a valuable tool that allows precise diagnosis of various endouterine pathologies. In our study, the sensitivity of hysteroscopy was 97% and the specificity was 98.66%. Hence, we can conclude that it is highly accurate for evaluating endometrial pathologies. For obvious benign lesions, it also provides treatment in the same sitting, therefore avoiding an extensive, morbid, and expensive procedure like hysterectomy.

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“…uation among postmenopausal women is a topic of ongoing debate in the literature. 11,12 The development of equipment and techniques for office-based endometrial biopsy has generally replaced the need for diagnostic dilation and curettage. The results of our study reinforces the opinion that hysteroscopy is a sensitive and specific tool in diagnosing intrauterine space occupying lessions.…”

Section: Methodsmentioning

confidence: 99%

Role of Hysteroscopy in Evaluation of Postmenopausal Bleeding Hysteroscopy in Menopause

Korkmazer¹,

Solak²,

Üstünyurt³

et al. 2015

Turkiye Klinikleri J Gynecol Obst

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A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : As a possible sign of endometrial cancer postmenopausal bleeding should be evaluated carefully. Dilatation and curettage (D&C) is still gold standard for assessment of postmenopausal bleeding. The development of hysteroscopy has provided a minimally invasive approach for endometrial assessment. We aimed to correlate hysteroscopic impressions and pathological findings in postmenopausal bleeding in this study. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : This is a retrospective cross-sectional study. This study involves case records of one hundred thirteen women with postmenopausal bleeding. One hundred thirteen women with postmenopausal bleeding who underwent hysteroscopy with diagnostic D&C between January 2012 and January 2013 at Bursa Zübeyde Hanım Maternity Hospital, Department of Obstetrics and Gynecology. Sensitivity, specificity, positive (PPV) and negative (NPV) predictive values of hysteroscopy were calculated. D&C was set as the 'gold standard'. R Re es su ul lt ts s: : For the assessment of postmenopausal bleeding hysteroscopy has high sensitivity and specificity for endometrial space occupying lesions (polyp 100%, 93%; fibroid 100%, 91.8%). However for endometrial hyperplasia, hysteroscopy has low sensitivity (75%). C Co on nc cl lu us si io on n: : Hysteroscopy is a good diagnostic method especially for detecting intrauterine spaceoccupying (polyp, fibroid) lesions, but moderate for endometrial hyperplasia. Hysteroscopic view combined with hysteroscopy guided endometrial biopsy could be a gold standard for endometrial assessment in postmenopausal bleeding.

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Detection of Benign Intracavitary Lesions in Postmenopausal Women with Abnormal Uterine Bleeding: A Prospective Comparative Study on Outpatient Hysteroscopy and Blind Biopsy

Cited by 76 publications

References 22 publications

Investigation of Women with Postmenopausal Uterine Bleeding: Clinical Practice Recommendations

Investigation of Women with Postmenopausal Uterine Bleeding: Clinical Practice Recommendations

Hysteroscopy—A Mode of Screening Women with Postmenopausal Bleeding: Our Experience

Role of Hysteroscopy in Evaluation of Postmenopausal Bleeding Hysteroscopy in Menopause

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