Detection of bony defects around cementless acetabular components in total hip arthroplasty: A DEXA study on 10 human cadavers

Laursen, Mogens Berg; Nielsen, Poul; Søballe, Kjeld

doi:10.1080/17453670610045939

Cited by 5 publications

(3 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We went further in testing the reproducibility and quantifying of the model and concluded that it would be useful in detecting periacetabular osteolysis [9,10].…”

Section: Dexa Scanningmentioning

confidence: 99%

See 1 more Smart Citation

Bone remodelling around HA-coated acetabular cups

Laursen

Nielsen

Søballe

2006

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

This study was designed to investigate bone remodelling around the cup in cementless THA. Previous studies indicate an advantage of better sealing of the bone-prosthesis interface by HA/TCP coating of implants, inhibiting polyethylene-induced osteolysis. One hundred patients gave informed consent to participate in a controlled randomized study between porous coated Trilogy versus Trilogy Calcicoat (HA/TCP coated). The cup was inserted in press-fit fixation. The femoral component was a cementless porous coated titanium alloy stem (Bi-Metric), with a modular 28-mm CrCo head. The Harris Hip Score (HHS) and bone mineral density (BMD) determined by DEXA scanning were used to study the effect. Measurements revealed no difference between the two groups after 3 years either in the clinical outcome or in terms of periprosthetic bone density. Patients with a body mass index above normal regained more bone mineral than patients with normal weight. This finding supports the assumption that load is beneficial to bone remodelling.

show abstract

“…We went further in testing the reproducibility and quantifying of the model and concluded that it would be useful in detecting periacetabular osteolysis [9,10].…”

Section: Dexa Scanningmentioning

confidence: 99%

“…Measurements were performed with a dual energy X-ray absorptiometer (Norland XR-36 Bone Densitometer) as previously described [9,10]. We performed calibration daily, with two different phantoms, according to the instructions from the manufacturer.…”

Section: Dexa Scanningmentioning

confidence: 99%

Bone remodelling around HA-coated acetabular cups

Laursen

Nielsen

Søballe

2006

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

show abstract

“…Since osteolysis is implicated in the early phases of prosthetic loosening and failure, it is essential to accurately quantify periprosthetic osteolysis. Conventional radiology is not sensitive and accurate enough to detect small amounts of osteolysis, but dual energy x-ray absorptiometry (DEXA) is able to detect even small defects in the periprosthetic bone in the acetabulum [ 5 ]. In spite of the advantages of low wear and fewer dislocations, metal-on-metal hip prostheses increase systemic cobalt and chromium ion concentrations [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Large head metal-on-metal cementless total hip arthroplasty versus 28mm metal-on-polyethylene cementless total hip arthroplasty: design of a randomized controlled trial

Zijlstra

Bos

Raaij

2008

BMC Musculoskelet Disord

View full text Add to dashboard Cite

BMC Musculoskeletal Disorders Open Access Study protocolLarge head metal-on-metal cementless total hip arthroplasty versus 28mm metal-on-polyethylene cementless total hip arthroplasty: design of a randomized controlled trial Wierd P Zijlstra*, Nanne Bos and Jos JAM van Raaij Address: Department of Orthopaedic Surgery, Martini Hospital, PO Box 30.033, 9700 RM Groningen, the Netherlands Email: Wierd P Zijlstra* -wpzijlstra@hotmail.com; Nanne Bos -nannebos@hotmail.com; Jos JAM van Raaij -raayjjam@mzh.nl * Corresponding author Abstract Background: Osteoarthritis of the hip is successfully treated by total hip arthroplasty with metal-onpolyethylene articulation. Polyethylene wear debris can however lead to osteolysis, aseptic loosening and failure of the implant. Large head metal-on-metal total hip arthroplasty may overcome polyethylene wear induced prosthetic failure, but can increase systemic cobalt and chromium ion concentrations. The objective of this study is to compare two cementless total hip arthroplasties: a conventional 28 mm metalon-polyethylene articulation and a large head metal-on-metal articulation. We hypothesize that the latter arthroplasties show less bone density loss and higher serum metal ion concentrations. We expect equal functional scores, greater range of motion, fewer dislocations, fewer periprosthetic radiolucencies and increased prosthetic survival with the metal-on-metal articulation.Methods: A randomized controlled trial will be conducted. Patients to be included suffer from noninflammatory degenerative joint disease of the hip, are aged between 18 and 80 and are admitted for primary cementless unilateral total hip arthroplasty. Patients in the metal-on-metal group will receive a cementless titanium alloy acetabular component with a cobalt-chromium liner and a cobalt-chromium femoral head varying from 38 to 60 mm. Patients in the metal-on-polyethylene group will receive a cementless titanium alloy acetabular component with a polyethylene liner and a 28 mm cobalt-chromium femoral head. We will assess acetabular bone mineral density by dual energy x-ray absorptiometry (DEXA), serum ion concentrations of cobalt, chromium and titanium, self reported functional status (Oxford hip score), physician reported functional status and range of motion (Harris hip score), number of dislocations and prosthetic survival. Measurements will take place preoperatively, perioperatively, and postoperatively (6 weeks, 1 year, 5 years and 10 years).Discussion: Superior results of large head metal-on-metal total hip arthroplasty over conventional hip arthroplasty have been put forward by experts, case series and the industry, but to our knowledge there is no randomized controlled evidence. Conclusion:This randomized controlled study has been designed to test whether large head metal-onmetal cementless total hip arthroplasty leads to less periprosthetic bone density loss and higher serum metal ion concentrations compared to 28 mm metal-on-polyethylene cementless total hip arthroplasty.

show abstract