Wound infections caused by drug-resistant bacteria are a serious public health concern with the association in delayed wound healing, increased treatment cost and mortality. 1 Among Grampositive bacteria, Staphylococcus aureus is one of the utmost predominantly isolated bacteria from wound whereas, Pseudomonas aeruginosa is mostly prevalent amongst gram-negative bacteria. 2 In Nigeria, the prevalence of wound infection caused by drug-resistant bacteria is quite high as compared to other parts of the world. The prevalence of drug-resistant wound pathogen is reported at 70.1%; with frequently isolated pathogens such as S. aureus, P. aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, 3 and Escherichia coli. 4 The persistent rise of antimicrobial resistance in recent times impacts on wound infection. 5 Hence, it is imperative to explore new antimicrobials for treatment of wounds infected with drug-resistant bacteria.