Detection of Chemically-Induced Damage in Layered DNA Films with Co(bpy)33+ by Square-Wave Voltammetry

Electrochemical DNA Biosensors in Food Safety: Determination of Phenolic Compounds and Antioxidant Capacity in Foods and Beverages

“…Similar processes were observed for bpy complexes of Ru(II) [51][52][53] and phen complexes of Co(III) [54]. All the complexes mentioned are accumulated on the ds-DNA due to partial intercalation in open circuit.…”

Electrochemiluminescence Arrays for Studies of Metabolite‐related Toxicity

“…We previously reviewed research on cyt P450 catalysis in films on electrodes . Our early focus was achieving thin LbL film environments to facilitate reversible Fe III /Fe II electron transfer (ET) of cyt P450 on an electrode surface . However, this reduction in the natural catalytic pathway of cyt P450s is achieved by ET from cyt P450 reductase (CPR) that has previously accepted electrons from NADPH.…”

Electrochemical detection of in situ DNA damage induced by enzyme-catalyzed Fenton reaction. Part I: in phosphate buffer solution

“…However, all these methods are laborious time-consuming, or involve equipments with high cost. In contrast, electrochemical methods [18][19][20][21][22][23][24][25][26] provide an attractive, simple, inexpensive approach to monitor DNA damage, and have aroused great interests among researchers.…”

“…Liu et al [22] have reported that electrochemical current was observed though DNA duplexes by using methylene blue as an intercalator. Hu and coworkers [23] have showed that detecting DNA lesion has been extended using an anionic intercalator, 2, 6-anthraquinone disulphonic acid (AQDs). In our study, electroactive Co(bpy) 3 3+ provides a highly sensitive way to detect DNA damage, due to the different interactions of the probe with intact and damaged DNA [24].…”