Detection of chikungunya virus DNA using two-dimensional MoS2 nanosheets based disposable biosensor

Singhal, Chaitali; Khanuja, Manika; Chaudhary, Nahid; Pundir, C.S.; Narang, Jagriti

doi:10.1038/s41598-018-25824-8

Cited by 100 publications

(43 citation statements)

References 48 publications

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“…Furthermore, the ability to detect vector-borne diseases (such as Zika virus [128], Dengue virus [129], chikungunya [130], and yellow fever virus [131]) directly from crude human sample matrices (blood, urine and saliva) with a smartphone-based diagnostic platform demonstrates the possibility of a widespread clinical deployment [132] at home or at a (off-grid) emergency shelter.…”

Section: Biometric and Medical Iot Applicationsmentioning

confidence: 99%

A Review of the Internet of Floods: Near Real-Time Detection of a Flood Event and Its Impact

Ackere

Verbeurgt

Sloover

et al. 2019

Water

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Worldwide, flood events frequently have a dramatic impact on urban societies. Time is key during a flood event in order to evacuate vulnerable people at risk, minimize the socio-economic, ecologic and cultural impact of the event and restore a society from this hazard as quickly as possible. Therefore, detecting a flood in near real-time and assessing the risks relating to these flood events on the fly is of great importance. Therefore, there is a need to search for the optimal way to collect data in order to detect floods in real time. Internet of Things (IoT) is the ideal method to bring together data of sensing equipment or identifying tools with networking and processing capabilities, allow them to communicate with one another and with other devices and services over the Internet to accomplish the detection of floods in near real-time. The main objective of this paper is to report on the current state of research on the IoT in the domain of flood detection. Current trends in IoT are identified, and academic literature is examined. The integration of IoT would greatly enhance disaster management and, therefore, will be of greater importance into the future.

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Section: Biometric and Medical Iot Applicationsmentioning

confidence: 99%

A Review of the Internet of Floods: Near Real-Time Detection of a Flood Event and Its Impact

Ackere

Verbeurgt

Sloover

et al. 2019

Water

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“…The hybrid nanosheet containing 3DG-Au nanoparticles (Au NPs) provides a high surface area for immobilizing recognition probe and improved performance of the developed biosensor. Singhal et al applied methylene blue as a redox indicator for detection of chikungunya virus DNA [174]. For instance, nanostructured ZnO based DNA biosensor is fabricated for detection of bacterial meningitis [169].…”

Section: Electrochemical Genosensor For Detection Of Microorganismmentioning

confidence: 99%

Ultrasensitive Bioaffinity Electrochemical Sensors: Advances and New Perspectives

Alizadeh

Salimi

2018

Electroanalysis

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This article reviews recent advances and developments in the field of bioaffinity electrochemical sensors with emphasis on a subclass including immunosensors, aptasensors, genosensors and molecularly imprinted sensosr. Recent insights into novel fabrication methodologies and electrochemical techniques have resulted in the demonstration of biosensors able to detection of wide range of target analyte. It has been shown that due to their high specificity and sensitivity, they represent a great tool in practical applications. Furthermore, at last couple decades nanotechnology has become very popular in the sensor fields due to the high capacity of nanomaterials to immobilize of bioaffinity agents and also their inhibiting effects on denaturation of enzymes and other bioaffinity systems, which they could well have beneficial effects for the performance of these sensors. The main focus of this review is to discuss methods for immobilizing bioreceptors onto a solid support, introduction of nanomaterials for improve sensitivity of biosensor and various electrochemical sensing platforms. The use of biosensor in these applications is most appropriate, because the analysis of trace substances in medical and healthcare applications, environmental science, and food industries is so important. In addition, recent advances in nanomaterial‐mediated bioaffinity sensors used for onset biosensing, point‐of‐care testing and healthcare management are also highlighted.

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“…As the representative TMDC, MoS 2 shows a high carrier mobility (60 cm 2 /V s at 250 K), a layer-dependent bandgap (1.2-1.8 eV), a high transistor on/off ratio (~ 10 8 ), and reasonable environmental stability [11]. Recent reports have demonstrated that 2D MoS 2 is a desirable channel material in FET sensor with breakthroughs in sensing performance for various analytes including NO 2 [12][13][14][15], NH 3 [16,17], chemical vapor [18,19], metal ion [20][21][22], small molecule [23][24][25], as well as biomaterials such as nucleic acid [26][27][28][29], protein [30][31][32], and microorganism [33]. Compared with MOSFET sensors, 2D-TMDCbased FET sensors normally show higher sensitivities due to the 2D nanosheet structure of TMDC.…”

Section: Introductionmentioning

confidence: 99%

Environmental Analysis with 2D Transition-Metal Dichalcogenide-Based Field-Effect Transistors

2020

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• Recent advances of two-dimensional (2D) transition-metal dichalcogenide (TMDC)-based field-effect transistor (FET) sensors for environmental analysis are summarized. • Representative TMDC FET sensors in gaseous and aqueous media analysis are introduced. • Challenges and future research directions of 2D TMDC FET sensors are discussed. ABSTRACT Field-effect transistors (FETs) present highly sensitive, rapid, and in situ detection capability in chemical and biological analysis. Recently, two-dimensional (2D) transition-metal dichalcogenides (TMDCs) attract significant attention as FET channel due to their unique structures and outstanding properties. With the booming of studies on TMDC FETs, we aim to give a timely review on TMDCbased FET sensors for environmental analysis in different media. First, theoretical basics on TMDC and FET sensor are introduced. Then, recent advances of TMDC FET sensor for pollutant detection in gaseous and aqueous media are, respectively, discussed. At last, future perspectives and challenges in practical application and commercialization are given for TMDC FET sensors. This article provides an overview on TMDC sensors for a wide variety of analytes with an emphasize on the increasing demand of advanced sensing technologies in environmental analysis.

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Detection of chikungunya virus DNA using two-dimensional MoS2 nanosheets based disposable biosensor

Cited by 100 publications

References 48 publications

A Review of the Internet of Floods: Near Real-Time Detection of a Flood Event and Its Impact

A Review of the Internet of Floods: Near Real-Time Detection of a Flood Event and Its Impact

Ultrasensitive Bioaffinity Electrochemical Sensors: Advances and New Perspectives

Environmental Analysis with 2D Transition-Metal Dichalcogenide-Based Field-Effect Transistors

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