Detection of clinically significant prostate cancer by transperineal multiparametric magnetic resonance imaging-ultrasound fusion targeted prostate biopsy in smaller prostates

Dahl, Douglas M.; Kim, Michelle M.; Wu, Shulin; Lin, Sharron X.; Crotty, Rory; Cornejo, Kristine M.; Harisinghani, Mukesh G.; Feldman, Adam S.; Wu, Chin Lee

doi:10.1016/j.urolonc.2022.07.011

Cited by 2 publications

(11 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of the 30 articles, 21 studies were conducted prospectively (none randomized) [ 21 , 22 , 24 , 27 , 28 , 29 , 30 , 32 , 33 , 34 , 35 , 38 , 39 , 40 , 41 , 42 , 43 , 48 , 49 , 50 ] and nine retrospectively [ 23 , 25 , 26 , 31 , 36 , 37 , 44 , 45 , 47 ].…”

Section: Evidence Synthesismentioning

confidence: 99%

“…Eight series were multicenter [ 21 , 24 , 25 , 26 , 34 , 35 , 40 , 49 ] while the remaining 22 were from a single center [ 22 , 23 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 36 , 37 , 38 , 39 , 40 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 50 ]. Overall, the characteristics and biopsy results of 11,313 patients were analyzed.…”

Section: Evidence Synthesismentioning

confidence: 99%

“…The study population included two articles [ 42 , 45 ] on patients with naïve biopsy, three articles [ 34 , 35 , 48 ] on patients with previous negative biopsy, twelve articles [ 22 , 23 , 24 , 26 , 28 , 30 , 32 , 33 , 36 , 41 , 43 , 44 ] on patients with naïve biopsy and previous negative biopsy, eleven studies [ 27 , 29 , 31 , 37 , 38 , 39 , 40 , 46 , 47 , 49 , 50 ] on patients with naïve biopsy and previous negative biopsy and patients in active surveillance (AS) and finally, two articles by Jacewicz et al [ 21 , 25 ] on patients with no prior biopsy, patients with prior negative biopsy, AS, focal therapy (FT) control, and SBRT recurrence. These data are presented in Table 3 .…”

Section: Evidence Synthesismentioning

confidence: 99%

“…All resonances performed prior to the biopsies were carried out via 1.5 or 3.0 Tesla resonators scans and interpreted using the PI-RADS score Version 1.0 in 1 article [ 34 ], version 2.0 in 26 studies [ 21 , 22 , 23 , 24 , 25 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 46 , 47 , 48 , 50 ], and version 2.1 in 1 article [ 45 ]. In two series [ 26 , 49 ], the reading of the resonance was carried out using the Likert scale.…”

Section: Evidence Synthesismentioning

confidence: 99%

See 3 more Smart Citations

A Systematic Review of the Current Status of Magnetic Resonance–Ultrasound Images Fusion Software Platforms for Transperineal Prostate Biopsies

Paesano,

Catalá,

Tcholakian

et al. 2023

Cancers

View full text Add to dashboard Cite

Given this new context, our objective is to recognize the suitability of the currently available software for image fusion and the reported series using the transperineal route, as well as to generate new evidence on the complementarity of the directed and systematic biopsies, which has been established through the transrectal approach. Evidence acquisition: This systematic review, registered in Prospero (CRD42022375619), began with a bibliographic search that was carried out in PubMed, Cochrane, and Google Scholar databases. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) criteria and the studied eligibility based on the Participants, Intervention, Comparator, and Outcomes (PICO) strategy were followed. Warp analysis of selected studies was performed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. In addition, a Google search of all currently available fusion platforms was performed. Our Google search found 11 different commercially available robots to perform transperineal image fusion biopsies, of which 10 devices have published articles supporting their diagnostic effectiveness in transperineal prostate biopsies. Results: A total of 30 articles were selected and the characteristics and results of the biopsies of 11,313 patients were analyzed. The pooled mean age was 66.5 years (63–69). The mean pooled PSA level was 7.8 ng/mL (5.7–10.8). The mean pooled prostate volume was 45.4 cc. (34–56). The mean pooled PSA density was 0.17 (0.12–0.27). The overall cancer detection rate for all prostate cancers was 61.4%, while for csPCa it was 47.8%. PCa detection rate was more effective than that demonstrated in the systematic transrectal biopsy. However, the detection of csPCa in the systematic biopsy was only 9.5% in the reported series. To standardize our review, we grouped prostate cancer screening results according to the population studied and the software used. When the same populations were compared between elastic and rigid software, we found that rigid biopsies had a higher csPCa detection rate than biopsies with elastic fusion systems. Conclusion: Platforms performing prostate biopsy using transperineal image fusion have better detection rates of csPCa than systematic transrectal biopsies. Rigid fusion systems have a better csPCa detection rate than elastic ones. We found no diagnostic differences between the different types of robotic systems currently available. The complementarity of systematic biopsy has also been demonstrated in transperineal imaging fusion biopsies.

show abstract

Section: Evidence Synthesismentioning

confidence: 99%

Section: Evidence Synthesismentioning

confidence: 99%

Section: Evidence Synthesismentioning

confidence: 99%

Section: Evidence Synthesismentioning

confidence: 99%

See 2 more Smart Citations

A Systematic Review of the Current Status of Magnetic Resonance–Ultrasound Images Fusion Software Platforms for Transperineal Prostate Biopsies

Paesano,

Catalá,

Tcholakian

et al. 2023

Cancers

View full text Add to dashboard Cite

show abstract

“…Finally, in our study, using 0.15 ng/mL/cm 3 as PSAD cutoff value, we found that PASD by MRI PV providing the highest csPCa detection in RP specimens than by RP PV or RP weight (57.9%, 57.6%, and 45.4%, respectively). Our data suggested that presurgery MRI is an efficient method to obtain PSAD for further clinical management [33].…”

Section: Discussionmentioning

confidence: 99%

Estimated Prostate Volume by Semiautomatic Segmentation of MRI Is More Accurately Correlated with Radical Prostatectomy Specimen Weight than the Volume Calculated by Ellipsoid Formula

Wu,

Feldman,

Lin

et al. 2023

Urol Int

View full text Add to dashboard Cite

Introduction: Accurate in vivo prostate volume (PV) estimation is important for obtaining prostate-specific antigen density (PSAD) and further predicting clinically significant prostate cancer (csPCa). We aimed to evaluate the accuracy of multiparametric magnetic resonance imaging (mpMRI)-estimated PV compared to both volume and weight of radical prostatectomy (RP). Methods: We identified 310 PCa patients who underwent RP following combined targeted and systematic biopsy in our institution from September 2019 to February 2021. The MRI PV was determined using a semiautomated segmentation algorithm. RP PV was calculated using the prolate ellipsoid formula (length × width × height × π/6). Formula (prostate weight = [actual weight−3.8 g]/1.05 g/mL) was applied, and the resulting volume was used in further analysis. Results: The median PV from MRI, RP, and RP weight were 39 mL, 38 mL, and 44 mL, respectively. Spearman’s rank correlation coefficients (ρ) were 0.841 (MRI PV vs. RP weight), 0.758 (RP PV vs. RP weight), and 0.707 (MRI PV vs. RP PV) (all p < 0.001). Decreased correlation between the MRI PV and RP PV was observed in the larger (more than 55 mL) prostate. The PSAD derived from MRI PV showed most efficient to detect csPCa in RP specimen (57.9% vs. 57.6% vs. 45.4%). Conclusion: MRI PV is correlated better with RP weight than calculated RP PV, especially in larger prostate. The high csPCa detection rate in final pathology suggested that PSAD derived from MRI PV can be confidently used in clinical practice.

show abstract

Detection of clinically significant prostate cancer by transperineal multiparametric magnetic resonance imaging-ultrasound fusion targeted prostate biopsy in smaller prostates

Cited by 2 publications

References 30 publications

A Systematic Review of the Current Status of Magnetic Resonance–Ultrasound Images Fusion Software Platforms for Transperineal Prostate Biopsies

A Systematic Review of the Current Status of Magnetic Resonance–Ultrasound Images Fusion Software Platforms for Transperineal Prostate Biopsies

Estimated Prostate Volume by Semiautomatic Segmentation of MRI Is More Accurately Correlated with Radical Prostatectomy Specimen Weight than the Volume Calculated by Ellipsoid Formula

Contact Info

Product

Resources

About