Detection of Coronary Artery Stenoses by Contrast-Enhanced, Retrospectively Electrocardiographically-Gated, Multislice Spiral Computed Tomography

Achenbach, Stephan; Giesler, Tom; Ropers, Dieter; Ulzheimer, Stefan; Derlien, Hans; Schulte, Christoph; Wenkel, Evelyn; Moshage, Werner; Bautz, W.; Daniel, Werner G.; Kalender, Willi A.; Baum, Ulrich

doi:10.1161/01.cir.103.21.2535

Cited by 594 publications

(353 citation statements)

References 15 publications

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“…3 With four-slice CT, a sensitivity of 58-86% for the detection of coronary stenosis has been reported, [10][11][12][13][14] but up to 32% of the vessels had to be excluded from analysis because of a decreased image quality. 10 Using 16-slice CT, overall sensitivity including all segments was reported to be between 73 and 95%, depending on the diameter of the segment, the modality of analysis, and the patient selection criteria. [2][3][4]15 However, in some studies evaluation was limited to branches having a diameter .2 mm.…”

Section: Discussionmentioning

confidence: 99%

Accuracy of MSCT Coronary Angiography With 64-Slice Technology: First Experience

Leschka¹,

Alkadhi²,

Plass³

2005

ACC Current Journal Review

257

355

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Aims The aim of our study was to investigate the accuracy of 64-slice computed tomography (CT) for assessing haemodynamically significant stenoses of coronary arteries. Methods and results CT angiography was performed in 67 patients (50 male, 17 female; mean age 60.1 + 10.5 years) with suspected coronary artery disease and compared with invasive coronary angiography. All vessels !1.5 mm were considered for the assessment of significant coronary artery stenosis (diameter reduction .50%). Forty-seven patients were identified as having significant coronary stenoses on invasive angiography with 18% (176/1005) affected segments. None of the coronary segments needed to be excluded from analysis. CT correctly identified all 20 patients having no significant stenosis on invasive angiography. Overall sensitivity for classifying stenoses was 94%, specificity was 97%, positive predictive value was 87%, and negative predictive value was 99%. Conclusion Sixty-four-slice CT provides a high diagnostic accuracy in assessing coronary artery stenoses.

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Section: Discussionmentioning

confidence: 99%

Accuracy of MSCT Coronary Angiography With 64-Slice Technology: First Experience

Leschka¹,

Alkadhi²,

Plass³

2005

ACC Current Journal Review

257

355

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“…Initially, MDCT lacked the capacity to evaluate coronary artery stenosis, with diagnostic accuracies for four-slice MDCT ranging from 78% to 93% (3,4). Additionally, MDCT was unable to assess almost one-quarter of all coronary artery segments due to poor image quality.…”

Section: Assessment Of Significant Cad Using Mdctmentioning

confidence: 99%

Transitioning from 16-slice to 64-slice multidetector computed tomography for the assessment of coronary artery disease: Are we really making progress?

Khan

Rawal

Eisenberg

2009

Canadian Journal of Cardiology

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“…With the use of 4-slice MSCT scanners, promising results have been published; however, cardiac motion and calcium deposits in the coronary artery wall rendered a substantial number of scans incompletely interpretable. [1][2][3] …”

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confidence: 99%

Reliable Noninvasive Coronary Angiography With Fast Submillimeter Multislice Spiral Computed Tomography

et al. 2002

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Background-Multislice spiral computed tomography (MSCT) is a promising technique for noninvasive coronary angiography, although clinical application has remained limited because of frequently incomplete interpretability, caused by motion artifacts and calcifications. Methods and Results-In 59 patients (53 male, aged 58Ϯ12 years) with suspected obstructive coronary artery disease, ECG-gated MSCT angiography was performed with a 16-slice MSCT scanner (0.42-s rotation time, 12ϫ0.75-mm detector collimation). Thirty-four patients were given additional ␤-blockers (average heart rate: 56Ϯ6 min

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Detection of Coronary Artery Stenoses by Contrast-Enhanced, Retrospectively Electrocardiographically-Gated, Multislice Spiral Computed Tomography

Abstract: MSCT with retrospective ECG gating permits the detection of coronary artery stenoses with high accuracy if image quality is sufficient, but its clinical use may presently be limited due to degraded image quality in a substantial number of cases, mainly due to rapid coronary motion.

Cited by 594 publications

References 15 publications

Accuracy of MSCT Coronary Angiography With 64-Slice Technology: First Experience

Accuracy of MSCT Coronary Angiography With 64-Slice Technology: First Experience

Transitioning from 16-slice to 64-slice multidetector computed tomography for the assessment of coronary artery disease: Are we really making progress?

Reliable Noninvasive Coronary Angiography With Fast Submillimeter Multislice Spiral Computed Tomography

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