We first report GeV γ-ray emission from SNR G15.9+0.2 in this work. We find that its power-law spectral index is 2.13±0.05 with 13.29σ significance level, and the γ-ray emission can be characterized by a 2D Gauss spatial distribution, which has a better improvement than the case of a point source. Moreover, we find that its likely counterparts from radio, X-ray, and TeV energy bands are well coincident with its spatial location. Analyzing the variability from 12.4 years of the light curve (LC), we find that this LC exists weak variability with a 3.30σ variability significance level. Investigating the 2σ error region of its best-fit position, we do not find certified active galactic nuclei (AGNs) and AGNs' candidates from the region of this SNR, so we suggest that the new γ-ray emission is likely to originate from SNR G15.9+0.2. On this basis, we discussed the likely origins of its γ-ray radiation combined with the distribution of surrounding molecular clouds.