Detection of Human Brucellosis by Brucellacapt and Rose Bengal Test in the Endemic Area

Abstract

Objective: Although brucellosis is the most common zoonosis in the world, it remains an infectious disease that has not received sufficient attention. This study’s aim was to retrospectively examine the results of the Rose Bengal and Brucellacapt tests in serum samples from patients with a prior diagnosis of brucellosis sent to our laboratory in our province, a highly endemic area for brucellosis.
 Materials and Methods: Between June 2019 and June 2021, 7827 serum samples sent to the public health laboratory with a provisional diagnosis of brucellosis were evaluated. The Rose Bengal and Brucellacapt test (Vircell, Spain) was used diagnose infection. Samples with antibody titer ≥1/160 were considered positive. 
 Results: Of the 7827 samples included in the study, 354 (4.6%) of the total 7677 serum samples tested were RBT positive, 118 (3.1%) of the 3776 samples tested were BCAP positive, and 118 (3.3%) of the 3626 samples tested were both RBT and BCAP positive. It was found that seropositivity significantly higher in female patients (p