Detection of Hypovitaminosis D in Older Adults: A Classification Tree Analysis

Hamdan, Sarah; Roussel, L.; Gleyses, Xavier; Chevallereau, Gaëlle; Schott, Anne-Marie; Beauchet, Olivier; Annweiler, Cédric

doi:10.1111/jgs.12847

Cited by 7 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…20e28 None of them used ANN methods, but used conventional linear statistical methods. Specifically, the few previous studies in this area tested the performance of already existing dietary questionnaires, 22,23,25 general physical questionnaires, 27,28 or isolated questions 24,26 to detect hypovitaminosis D. Whatever the model tested, results showed rather good sensitivity to hypovitaminosis D (range, 46%e91%) 27,28 but only modest specificity (range, 35%e74%), 25,29 and each time only a single metrological quality was observed (either sensitive or specific). Thus, the results of the current study provide new insights into the identification of hypovitaminosis D in seniors by using a novel statistical approach and by exhibiting greater diagnostic efficiency than hitherto.…”

Section: Discussionmentioning

confidence: 87%

Derivation and Validation of a Clinical Diagnostic Tool for the Identification of Older Community-Dwellers With Hypovitaminosis D

Annweiler

Kabeshova

Legeay

et al. 2015

Journal of the American Medical Directors Association

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 87%

Derivation and Validation of a Clinical Diagnostic Tool for the Identification of Older Community-Dwellers With Hypovitaminosis D

Annweiler

Kabeshova

Legeay

et al. 2015

Journal of the American Medical Directors Association

Self Cite

View full text Add to dashboard Cite

“…Although numerous studies have examined the variables influencing serum 25(OH)D concentration, only few have attempted to identify hypovitaminosis D among older adults, and only two among geriatric patients [ 18 , 19 ]. Specifically, these two previous studies have tested the performance of an isolated question [ 18 ] or a general physical questionnaire [ 19 ] to detect hypovitaminosis D among in- and outpatients; but none has evaluated the different definitions of hypovitaminosis D, and none have used a complex algorithm based on non-linear models of feed forward artificial neural networks such as the VDSP [ 8 ]. Thus, the results of the present study provide new insights into the identification of hypovitaminosis D in geriatric patients by using a novel clinical tool, and by exhibiting greater diagnostic efficacy than that hitherto demonstrated.…”

Section: Discussionmentioning

confidence: 99%

Clinical Identification of Geriatric Patients with Hypovitaminosis D: The ‘Vitamin D Status Predictor for Geriatrics’ Study

et al. 2017

Self Cite

View full text Add to dashboard Cite

The 16-item Vitamin D Status Predictor (VDSP) tool identifies healthy older community-dwellers at risk of hypovitaminosis D and may guide the use of blood tests in this population. The objective of the present hospital-based study was to test the efficacy of the VDSP to identify geriatric patients with hypovitaminosis D. The study included 199 nonsupplemented geriatric in- and outpatients consecutively admitted to Angers University Hospital, France (mean ± SD, 82.0 ± 7.8 years; 53.3% female). Serum 25-hydroxyvitaminD (25(OH)D) was measured at the time of the physician-administered VDSP. Hypovitaminosis D was defined as serum 25(OH)D concentration ≤ 75 nmol/L for vitamin D insufficiency, 25(OH)D ≤ 50 nmol/L for vitamin D deficiency, and 25(OH)D ≤ 25 nmol/L for severe vitamin D deficiency. We found that 184 participants (92.4%) had vitamin D insufficiency, 136 (68.3%) had vitamin D deficiency, and 67 (33.7%) had severe vitamin D deficiency. The VDSP identified severe vitamin D deficiency with an area under curve (AUC) = 0.83 and OR = 24.0. The VDSP was able to identify vitamin D deficiency and vitamin D insufficiency with less accuracy (AUC = 0.71 and AUC = 0.73, respectively). In conclusion, the 16-item VDSP is a short questionnaire that accurately identifies geriatric patients with severe vitamin D deficiency. This tool may guide the use of blood collection for determining geriatric patients’ vitamin D status.

show abstract

“…However, when we categorized studies by age (<50 years and !50 years) and performed a subgroup analysis, VD3S was found to significantly reduce SBP and DBP in participants aged !50 years. This may be because elderly people commonly have vitamin D deficiency [57,58] and often suffer from HTN [33].…”

Section: Discussionmentioning

confidence: 99%

Effect of vitamin D3 supplementation on blood pressure in adults: An updated meta-analysis

Golzarand

Shab‐Bidar

Koochakpoor

et al. 2016

Nutrition, Metabolism and Cardiovascular Diseases

View full text Add to dashboard Cite

A total of 30 RCTs with 41 arms including 4744 participants were included. The mean duration of the studies was 5.6 ± 4.0 months, and doses of VD3S varied between 200 and 12,000 IU/day. VD3S had no effect on SBP (-0.68 mmHg, 95%CI: -2.19 to 0.84), and DBP (-0.57 mmHg, 95%CI: -1.36 to 0.22). Subgroup analysis revealed that daily vitamin D3 therapy at a dose of >800 IU/day for <6 months in subjects ≥50 years old reduced both SBP and DBP (p < 0.001). In addition, VD3S showed hypotensive effects in healthy subjects and hypertensive patients, but a hypertensive effect in overweight and obese subjects. However, after excluding overweight and obese subjects, VD3S significantly reduced SBP and DBP. VD3S in combination with calcium supplementation significantly elevated SBP (3.64 mmHg, 95%CI: 3.15-4.13) and DBP (1.71 mmHg, 95%CI: 1.25-2.18). No evidence of publication bias was found. The effects of VD3S on blood pressure depend on dose of supplementation, treatment regimens, trial duration, and population subgroup. Supplementation may be beneficial at daily doses >800 IU/day for <6 months in subjects ≥50 years old.

show abstract

Detection of Hypovitaminosis D in Older Adults: A Classification Tree Analysis

Cited by 7 publications

References 9 publications

Derivation and Validation of a Clinical Diagnostic Tool for the Identification of Older Community-Dwellers With Hypovitaminosis D

Derivation and Validation of a Clinical Diagnostic Tool for the Identification of Older Community-Dwellers With Hypovitaminosis D

Clinical Identification of Geriatric Patients with Hypovitaminosis D: The ‘Vitamin D Status Predictor for Geriatrics’ Study

Effect of vitamin D3 supplementation on blood pressure in adults: An updated meta-analysis

Contact Info

Product

Resources

About