Detection of <i>Chlamydia psittaci</i> in Belgian cattle with signs of respiratory disease and milk drop syndrome

Loo, H. Van; Pardon, Bart; Schutter, Peter De; Bleecker, Koen De; Vanrompay, Daisy; Deprez, Piet; Maris, Jo

doi:10.1136/vr.102527

Cited by 8 publications

(8 citation statements)

References 21 publications

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“…C. psittaci has been detected in many species, including cattle, buffalo, goats, sheep and horses [13][14][15][16]. Infection in livestock can be associated with respiratory, intestinal or arthritic diseases and also abortion [17].…”

Section: Introductionmentioning

confidence: 99%

A 25-year retrospective study of Chlamydia psittaci in association with equine reproductive loss in Australia

Akter

Sansom

El-Hage

et al. 2021

Journal of Medical Microbiology

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Introduction. Chlamydia psittaci is primarily a pathogen of birds but can also cause disease in other species. Equine reproductive loss caused by C. psittaci has recently been identified in Australia where cases of human disease were also reported in individuals exposed to foetal membranes from an ill neonatal foal in New South Wales. Hypothesis/Gap Statement. The prevalence of C. psittaci in association with equine reproductive over time and in different regions of Australia is not known. Aim. This study was conducted to detect C. psittaci in equine abortion cases in Australia using archived samples spanning 25 years. Methodology. We tested for C. psittaci in 600 equine abortion cases reported in Australia between 1994 to 2019 using a Chlamydiaceae real-time quantitative PCR assay targeting the 16S rRNA gene followed by high-resolution melt curve analysis. Genotyping and phylogenetic analysis was performed on positive samples. Results. The overall prevalence of C. psittaci in material from equine abortion cases was 6.5 %. C. psittaci -positive cases were detected in most years that were represented in this study and occurred in Victoria (prevalence of 7.6 %), New South Wales (prevalence of 3.9 %) and South Australia (prevalence of 15.4 %). Genotyping and phylogenetic analysis showed that the C. psittaci detected in the equine abortion cases clustered with the parrot-associated 6BC clade (genotype A/ST24), indicating that infection of horses may be due to spillover from native Australian parrots. Conclusion. This work suggests that C. psittaci has been a signiﬁcant agent of equine abortion in Australia for several decades and underscores the importance of taking appropriate protective measures to avoid infection when handling equine aborted material.

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Section: Introductionmentioning

confidence: 99%

A 25-year retrospective study of Chlamydia psittaci in association with equine reproductive loss in Australia

Akter

Sansom

El-Hage

et al. 2021

Journal of Medical Microbiology

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“…The significance of C. psittaci in these diseases has often been unclear due to co-infection with various infectious agents, including other Chlamydia spp. 14 , 16 . C. pneumoniae 17 , 18 as well as C. abortus (co-infecting with C. psittaci ) 11 were reported in association with respiratory infections in both diseased and healthy horses, whereas C. abortus DNA (in co-infection with C. suis and C. psittaci ) was also detected in equine placental samples 19 .…”

Section: Introductionmentioning

confidence: 99%

An epizootic of Chlamydia psittaci equine reproductive loss associated with suspected spillover from native Australian parrots

Jenkins

Jelocnik

Micallef

et al. 2018

Emerging Microbes & Infections

118

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Chlamydia psittaci is an avian pathogen capable of spill-over infections to humans. A parrot C. psittaci strain was recently detected in an equine reproductive loss case associated with a subsequent cluster of human C. psittaci infections. In this study, we screened for C. psittaci in cases of equine reproductive loss reported in regional New South Wales, Australia during the 2016 foaling season. C. psittaci specific-PCR screening of foetal and placental tissue samples from cases of equine abortion (n = 161) and foals with compromised health status (n = 38) revealed C. psittaci positivity of 21.1% and 23.7%, respectively. There was a statistically significant geographical clustering of cases ~170 km inland from the mid-coast of NSW (P < 0.001). Genomic analysis and molecular typing of C. psittaci positive samples from this study and the previous Australian equine index case revealed that the equine strains from different studs in regional NSW were clonal, while the phylogenetic analysis revealed that the C. psittaci strains from both Australian equine disease clusters belong to the parrot-associated 6BC clade, again indicative of spill-over of C. psittaci infections from native Australian parrots. The results of this work suggest that C. psittaci may be a more significant agent of equine reproductive loss than thought. A range of studies are now required to evaluate (a) the exact role that C. psittaci plays in equine reproductive loss; (b) the range of potential avian reservoirs and factors influencing infection spill-over; and (c) the risk that these equine infections pose to human health.

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“…In addition to humans, C. psittaci has been detected in other mammals, including ruminants and horses 7‐10 . In animals, respiratory, intestinal, arthritic and reproductive diseases can occur due to C. psittaci infection 11 .…”

Section: Case Report Introductionmentioning

confidence: 99%

“…In addition to humans, C. psittaci has been detected in other mammals, including ruminants and horses. [7][8][9][10] In animals, respiratory, intestinal, arthritic and reproductive diseases can occur due to C. psittaci infection. 11 Horses are considered to be occasional hosts of C. psittaci, and infection can result in pneumonia, conjunctivitis, polyarthritis or abortion.…”

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confidence: 99%

Chlamydia psittaci: a suspected cause of reproductive loss in three Victorian horses

et al. 2020

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Chlamydia psittaci was detected by PCR in the lung and equine foetal membranes of two aborted equine foetuses and one weak foal from two different studs in Victoria, Australia. The abortions occurred in September 2019 in two mares sharing a paddock northeast of Melbourne. The weak foal was born in October 2019 in a similar geographical region and died soon after birth despite receiving veterinary care. The detection of C. psittaci DNA in the lung and equine foetal membranes of the aborted or weak foals and the absence of any other factors that are commonly associated with abortion or neonatal death suggest that this pathogen may be the cause of the reproductive loss. The detection of C. psittaci in these cases is consistent with the recent detection of C. psittaci in association with equine abortion in New South Wales. These cases in Victoria show that C. psittaci, and the zoonotic risk it poses, should be considered in association with equine reproductive loss in other areas of Australia.

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Detection of Chlamydia psittaci in Belgian cattle with signs of respiratory disease and milk drop syndrome

Cited by 8 publications

References 21 publications

A 25-year retrospective study of Chlamydia psittaci in association with equine reproductive loss in Australia

A 25-year retrospective study of Chlamydia psittaci in association with equine reproductive loss in Australia

An epizootic of Chlamydia psittaci equine reproductive loss associated with suspected spillover from native Australian parrots

Chlamydia psittaci: a suspected cause of reproductive loss in three Victorian horses

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