“…This method has been shown to be sensitive for the detection of early incipient lesions selin de Jong et al, 1995;Ando et al, 1997Ando et al, , 2001Ando et al, , 2004bAngmar-Mansson and ten Bosch, 2001;Shi et al, 2001;Tranaeus et al, 2001;Amaechi et al, 2003;Gonzalez-Cabezas et al, 2003;Heinrich-Weltzien et al, 2005;Stookey, 2005;Pretty, 2006;Pretty and Ellwood, 2007], but it is subject to confounding effects of saliva [Amaechi and Higham, 2002], drying time [Pretty et al, 2004], angulation [Buchalla et al, 2002;Ando et al, 2004a] and stain [Shi et al, 2001] among others factors [Heinrich-Weltzien et al, 2005]. Additionally, although QLF parameters (lesion depth expressed as ⌬ F and lesion volume expressed as ⌬ Q) have been shown to have a higher sensitivity when compared to other methods for detection of early caries lesions [Ferreira Zandoná et al, 2003] because the QLF analysis software detects any change in pixel values as demineralization, their specificity is greatly compromised.…”