Detection of liver neoplasms: Techniques and outcomes

Baron, Richard L.

doi:10.1007/bf00198188

Cited by 18 publications

(3 citation statements)

References 32 publications

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“…he liver is both a principal site for primary malignancies [1] and a major target for metastatic disease from primary tumors elsewhere in the body [2,3]. At the same time, the incidence of benign hepatic lesions is comparatively high in the adult population [4].…”

mentioning

confidence: 99%

Evaluation of the Accuracy of Gadobenate Dimeglumine-Enhanced MR Imaging in the Detection and Characterization of Focal Liver Lesions

Pirovano

Vanzulli

Martí‐Bonmatí

et al. 2000

American Journal of Roentgenology

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mentioning

confidence: 99%

Evaluation of the Accuracy of Gadobenate Dimeglumine-Enhanced MR Imaging in the Detection and Characterization of Focal Liver Lesions

Pirovano

Vanzulli

Martí‐Bonmatí

et al. 2000

American Journal of Roentgenology

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“…The liver is both a principal site of primary malignancies and a major target of metastatic disease from almost any primary malignant neoplasm 1 . In addition, the incidence of benign hepatic lesions is high in the adult population 2 – 4 . With remarkable advances in diagnostic imaging of the liver, small hepatic hypovascular lesions are increasingly being detected.…”

Section: Introductionmentioning

confidence: 99%

MRI characteristics for the differential diagnosis of benign and malignant small solitary hypovascular hepatic nodules

Qian

Li²,

Ji³

et al. 2016

European Journal of Gastroenterology &Amp; Hepatology

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PurposeTo compare the MRI findings of benign and malignant solitary hypovascular hepatic nodules and identify the differentiating features.Materials and methodsA total of 135 patients with solitary hypovascular hepatic lesions up to 3 cm (mass forming intrahepatic cholangiocarcinoma, n=29; metastases, n=26; inflammatory pseudotumors and solitary necrotic nodule, n=48; and hemangioma, n=32) were assessed. MRI findings were analyzed, and lesions were scored for peripheral and intratumoral appearance and enhancement patterns.ResultsUnivariate and multivariate analyses showed that the most common findings for benign lesions were subcapsular, sharp margin, homogeneous, marked high signal on T2WI, mild hyperintensity on T2WI, increasing intensity of peripheral globular enhancement, and persistent central septum-like linear enhancement on delayed phase (P<0.05). An area under the curve of 0.955 was obtained for differentiating malignant from benign nodules using the combined imaging features of ill-defined margins, heterogeneity, decreasing intensity of peripheral rim-like enhancement, and central increasing intensity of patchy enhancement. Interobserver agreement was good, ranging from 0.72 to 1.00.ConclusionMRI may be a useful noninvasive method for determining whether hypovascular hepatic nodules are malignant or benign.

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“…Post-contrast imaging has been shown to be superior to conventional plain MR imaging in detecting hepatic lesions [7] . It is known, however, that 40%-60% of cancer nodules, especially those in cirrhotic liver that are smaller than 10 mm, are missed at ultrasonography (US), computed tomography (CT) [8] , and MR [9] . Given this background, a possible solution to this problem is the use of liver-specific MR contrast materials: that is, agents that are targeted to either the hepatocytes or the Kupffer cells.…”

Section: Introductionmentioning

confidence: 99%

FerucarbotranversusGd-DTPA-enhanced MR imaging in the detection of focal hepatic lesions

Cheng

Zeng²,

Yan³

et al. 2007

WJG

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Detection of liver neoplasms: Techniques and outcomes

Cited by 18 publications

References 32 publications

Evaluation of the Accuracy of Gadobenate Dimeglumine-Enhanced MR Imaging in the Detection and Characterization of Focal Liver Lesions

Evaluation of the Accuracy of Gadobenate Dimeglumine-Enhanced MR Imaging in the Detection and Characterization of Focal Liver Lesions

MRI characteristics for the differential diagnosis of benign and malignant small solitary hypovascular hepatic nodules

FerucarbotranversusGd-DTPA-enhanced MR imaging in the detection of focal hepatic lesions

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