Detection of Local Recurrence in Patients with Head and Neck Squamous Cell Carcinoma Using Voxel-Based Color Maps of Initial and Final Area under the Curve Values Derived from DCE-MRI

Abstract

BACKGROUND AND PURPOSE: Early detection of local recurrence is important to increase the chance of cure because local recurrence is the main cause of treatment failure in head and neck squamous cell carcinoma. We evaluated the added value of voxel-based color maps of dynamic contrast-enhanced MR imaging compared with conventional MR imaging alone for detecting local recurrence of head and neck squamous cell carcinoma. MATERIALS AND METHODS: We retrospectively enrolled 63 consecutive patients with head and neck squamous cell carcinoma after definitive treatment and posttreatment surveillance MR imaging studies that demonstrated focal enhancement at the primary site. Three independent readers assessed conventional MR imaging and a pair of color maps of initial and final 90-second time-signal intensity areas under the curve from dynamic contrast-enhanced MR imaging. The sensitivities, specificities, and accuracies of both conventional MR imaging alone and combined interpretation of conventional and dynamic contrast-enhanced MR imaging were assessed using the clinicopathologic diagnosis as the criterion standard. statistics were used to evaluate interreader agreement.

Post-therapeutic detection of local tumor persistence of head and neck cancer: the value of routine control endoscopy with biopsy and medical imaging

“…Medical imaging reports predominantly obtained from CT-scans (n=85; 85%) in addition to fewer MRI-scans (n=15; 15%) were classified according to the internationally applied RECIST imaging scale, as well as a scale by Lee et al and a self-developed Engert-scale (Table 4). 4,5 Diagnostic accuracy was determined as shown in Table 5.…”

“…Besides the internationally applied RECIST-scale, a similar categorization was created by Lee et al when interpreting conventional MRI scans for the detection of tumor recurrence. 5 Due to the retrospective nature of our study we had to add further groups to allocate imaging reports, where no differentiation was possible and created the Engert-scale. The authors believe that imaging reports tend to keep a backdoor for uncertainty to evade possible (legal) consequences.…”

CT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic Review

“…Detailed information about our own MR imaging parameters was the same as that published in previous articles by our group. 5,6 On MR imaging, 2 glomangiopericytomas showed homogeneous hyperintensity on T2WI, 1 glomangiopericytoma showed intermediate signal intensity, and 1 glomangiopericytoma showed heterogeneous intermediate-to-high signal intensity. All glomangiopericytomas revealed vascular signal voids on T2WI.…”