Detection of maternal serum hCG glycoform variants in the second trimester of pregnancies affected by Down syndrome using a lectin immunoassay

Abstract

Maternal serum GlyhCG, as measured by the sialic acid-binding lectin immunoassay is unlikely to be of additional value when screening for Down syndrome in the second trimester.

Determination of Trace Alkaline Phosphatase by Solid‐Substrate Room‐Temperature Phosphorimetry Based on Triticum vulgare Lectin Labeled with Fullerenol

“…Alkaline phosphatase (ALP) is an important enzyme in both clinical diagnosis and life science, and it has been applied to signal amplification and enzyme immunoassay in biochemical analysis [7]. There are several methods using lectin to determine enzyme, glycoprotein, and other glycosylchain structures in serum, such as the electrochemistry luminescent method [8], enzyme-linked immunoassay [9], fluorescence immunity method [10], affinity chromatography method [11], affinity immunity electrophoresis self-developed method [12], chemiluminescent immunoassay [13], capillary electrophoresis -ultraviolet spectroscopy method (detection limit: 7.6 Â 10 À 12 mol l À 1…”