Detection of Mercury Ion with High Sensitivity and Selectivity Using a DNA/Graphene Oxide Hybrid Immobilized on Glass Slides

Gao, Li; Lv, Qiuxiang; Ni, Xiaomin; Lin, Yuanwei; Lin, Feng; Han, Bangxing

doi:10.3390/bios11090300

Cited by 9 publications

(3 citation statements)

References 37 publications

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“…The cutting rate increases as the Hg 2+ concentration increases, whereas the fluorescence intensity of the corresponding slide decreases. As a result, the analytes can be measured by comparing the fluorescence intensity before and after the addition of Hg 2+ [ 126 ].…”

Section: Optical Biosensor Detection Of Heavy Metalsmentioning

confidence: 99%

Recent Advances in the Application of Bionanosensors for the Analysis of Heavy Metals in Aquatic Environments

Wu,

Ga,

Wang

et al. 2023

Molecules

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Heavy-metal ions (HMIs) as a pollutant, if not properly processed, used, and disposed of, will not only have an influence on the ecological environment but also pose significant health hazards to humans, making them a primary factor that endangers human health and harms the environment. Heavy metals come from a variety of sources, the most common of which are agriculture, industry, and sewerage. As a result, there is an urgent demand for portable, low-cost, and effective analytical tools. Bionanosensors have been rapidly developed in recent years due to their advantages of speed, mobility, and high sensitivity. To accomplish effective HMI pollution control, it is important not only to precisely pinpoint the source and content of pollution but also to perform real-time and speedy in situ detection of its composition. This study summarizes heavy-metal-ion (HMI) sensing research advances over the last five years (2019–2023), describing and analyzing major examples of electrochemical and optical bionanosensors for Hg2+, Cu2+, Pb2+, Cd2+, Cr6+, and Zn2+.

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Section: Optical Biosensor Detection Of Heavy Metalsmentioning

confidence: 99%

Recent Advances in the Application of Bionanosensors for the Analysis of Heavy Metals in Aquatic Environments

Wu,

Ga,

Wang

et al. 2023

Molecules

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“…The presence of heavy metal mercury ions in environmental pollutants and foodstuffs are of great concern (Irvine et al, 2017;Gao et al, 2021). Hg 2+ is difficult to decomposed in the environment, can easily bioaccumulate in the human body and causing seriously harm to creatures and human beings (Liu et al, 2013;Ping et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Quantitative Visual Detection of Mercury Ions With Ratiometric Fluorescent Test Paper Sensor

Fan

Pan²,

Wang

et al. 2022

Front. Chem.

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A novel ratiometric fluorescence probe based on nitrogen-doped blue carbon dots (NCDs) and red gold nanoclusters (Au NCs) for mercuric ion (Hg2+) has been prepared and characterized. A user friendly fluorescent test paper based sensor combined with smartphone was fabricated for rapid visual and quantitative detection. Hg2+ can specifically bind to Au+ on the surface of Au NCs, leading to the quench of red fluorescence while the fluorescence intensity of the NCDs with blue fluorescence remained unchanged as a internal standard signal. The implement of paper-based sensor address some common drawback in analytical process such as the detection time, analysis cost. In a further demonstration, a homemade detection device with smartphone was used to qualify the Hg2+. After adding different concentration of Hg2+, red, purple, and blue colors were obtained on the detection zones of the fluorescent test paper. The Android App Color Grab was used to identify the red, green and blue (RGB) values of fluorescent color. The rapid visual and quantitative detection of Hg2+ was accomplished with the detection limit of 2.7 nM for fluorescence, 25 nM for smartphone and 32 nM for paper strip. The developed multi-mode detection platform was successfully applied to the detection of mercury ions in water samples with acceptable recoveries. The NCDs and Au NCs probe facilitate the one-site environmental monitoring for Hg2+ with “naked-eye” and smartphone.

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“…The surface of GO is rich in hydrophilic groups such as alkyl groups, epoxy groups, and carboxyl groups, which can be evenly dispersed in water. Therefore, GO-based sensors have attracted special attention, due to their short assay time, relatively low cost, and no requirement for skillful technicians [18][19][20][21][22][23]. The carboxyl groups on the surface of GO conjugate with the aminomodified aptamer, and therefore, the aptamer fixes on the surface of GO.…”

Section: Introductionmentioning

confidence: 99%

Thrombin Determination Using Graphene Oxide Sensors with Co-Assisted Amplification

Liu

Shi

et al. 2022

Micromachines

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Graphene oxide (GO) is widely used in sensors. The detection of proteins based on bare GO has been developed; however, the detection sensitivity needs to be improved. In this paper, a novel GO-DNA sensor for thrombin detection was developed using an aptamer linked to the surface of GO. Polyethylene glycol (PEG) was further used to prevent thrombin from nonspecific adsorption and to improve the sensitivity of the sensor for detection of thrombin. In order to improve the limit of detection for thrombin, we developed a GO and RecJf exonuclease co-assisted signal amplification strategy, and a detection limit of 24.35 fM for thrombin was achieved using this strategy. The results show that it is a promising method in analytical applications.

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Detection of Mercury Ion with High Sensitivity and Selectivity Using a DNA/Graphene Oxide Hybrid Immobilized on Glass Slides

Cited by 9 publications

References 37 publications

Recent Advances in the Application of Bionanosensors for the Analysis of Heavy Metals in Aquatic Environments

Recent Advances in the Application of Bionanosensors for the Analysis of Heavy Metals in Aquatic Environments

Quantitative Visual Detection of Mercury Ions With Ratiometric Fluorescent Test Paper Sensor

Thrombin Determination Using Graphene Oxide Sensors with Co-Assisted Amplification

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