2024
DOI: 10.3389/fimmu.2024.1252258
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Detection of minimal residual disease in acute myeloid leukemia: evaluating utility and challenges

Noemí Álvarez,
Alejandro Martín,
Sara Dorado
et al.

Abstract: This study discusses the importance of minimal residual disease (MRD) detection in acute myeloid leukemia (AML) patients using liquid biopsy and next-generation sequencing (NGS). AML prognosis is based on various factors, including genetic alterations. NGS has revealed the molecular complexity of AML and helped refine risk stratification and personalized therapies. The long-term survival rates for AML patients are low, and MRD assessment is crucial in predicting prognosis. Currently, the most common methods fo… Show more

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