Detection of New Five Tri-allelic Patterns at Penta D Locus in Autosomal STRs during Establishment of Genetic Fingerprint Database for the Iraqi Security Forces

Salih, Esam Ghazi Mohammed; Nader, Mohammed Ibrahim; Alzubaidi, Mohammed; Mahmood, Hanan K.; Salih, Khalifah Mahdi; Hasan, Dhurgham H.

doi:10.9734/bpi/pramr/v3/3949c

Perspective of Recent Advances in Medical Research Vol. 3 2023

DOI: 10.9734/bpi/pramr/v3/3949c

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Detection of New Five Tri-allelic Patterns at Penta D Locus in Autosomal STRs during Establishment of Genetic Fingerprint Database for the Iraqi Security Forces

Esam Ghazi Mohammed Salih

Mohammed Ibrahim Nader

Mohammed Alzubaidi

et al.

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Tri-Allelic Autosomal STR Patterns Observed in Pakistani Population during Forensic Case Work

Saeed,

Ahmad,

Ahmad

et al. 2023

AJFSFM

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The tri-allelic pattern is a genotyping abnormality that can be observed during routine short tandem repeat (STR) profiling in the field of forensic science. Fourteen tri-allelic patterns have been observed in nine different loci during routine forensic casework consisting of 20,000 STR profiles. All these 20,000 STR unrelated profiles were profiled using AmpFlSTR Identifiler Plus® and Global Filer® kits. Tri-allelic patterns can be divided into two types based on RFUs (relative fluorescent units) in peaks of three component alleles. Unequal RFUs of all three peaks are observed in the Type-I pattern, whereas in the Type-II pattern, RFUs of all three peaks are nearly equal. A total of nine novel tri-allelic genotypes were observed out of 20,000 unrelated individuals in the Pakistani population. All of these forensic cases belonged to the Type-I pattern which means that the sum of the height of two smaller peaks is nearly equal to the height of the third larger peak. The frequency of occurrence for all these patterns was compared with already reported data. In this study, eight novel tri-allelic patterns have been reported which are not listed in the National Institute of Standards and Technology (NIST) database as well as in any published article.

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Tri-Allelic Autosomal STR Patterns Observed in Pakistani Population during Forensic Case Work

Saeed,

Ahmad,

Ahmad

et al. 2023

AJFSFM

View full text Add to dashboard Cite

show abstract

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Detection of New Five Tri-allelic Patterns at Penta D Locus in Autosomal STRs during Establishment of Genetic Fingerprint Database for the Iraqi Security Forces

Cited by 1 publication

References 0 publications

Tri-Allelic Autosomal STR Patterns Observed in Pakistani Population during Forensic Case Work

Tri-Allelic Autosomal STR Patterns Observed in Pakistani Population during Forensic Case Work

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