2020
DOI: 10.15171/jlms.2020.03
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Detection of Nicotine Effect on Colon Cells in a Plasmonic Platform

Abstract: Introduction: Smoking as one of the causes of various diseases has encouraged worldwide studies on its adverse pharmacological effects on different organs. Nicotine may influence the smooth muscles of the colon and subsequently the gut motility, which leads to a change in the moving rate of digested material through the gastrointestinal tract. Methods: Among various techniques, optical detection methods benefit from non-contact and highsensitivity for studying the early effect of nicotine on the cells. Thus, w… Show more

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Cited by 5 publications
(2 citation statements)
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“…There are many methods to detect nicotine from biological biofluids such as blood, urine, or saliva tests. One of the fast, precise methods is using optical methods such as the surface plasmon resonance (SPR) technique . The SPR technique, as a label-free and real-time technique, can detect the interaction between the biological samples and the metallic interface with high resolution .…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…There are many methods to detect nicotine from biological biofluids such as blood, urine, or saliva tests. One of the fast, precise methods is using optical methods such as the surface plasmon resonance (SPR) technique . The SPR technique, as a label-free and real-time technique, can detect the interaction between the biological samples and the metallic interface with high resolution .…”
Section: Introductionmentioning
confidence: 99%
“…One of the fast, precise methods is using optical methods such as the surface plasmon resonance (SPR) technique. 1 The SPR technique, as a label-free and real-time technique, can detect the interaction between the biological samples and the metallic interface with high resolution. 2 If a fluorophore is placed close to the metallic surface, the resonant coupling of the fluorescence signal and the surface plasmon (SP) mode increases the interaction and amplifies the fluorescence signal because of the enhancement in intensity of the electromagnetic field on a metallic surface and subsequent increase in the excitation rate of the fluorophore.…”
Section: Introductionmentioning
confidence: 99%