Detection of nitro-organic and peroxide explosives in latent fingermarks by DART- and SALDI-TOF-mass spectrometry

Rowell, Frederick J.; Seviour, John; Lim, Angelina Yimei; Elumbaring-Salazar, Cheryl Grace; Loke, Jason; Ma, Jan

doi:10.1016/j.forsciint.2012.04.007

Cited by 106 publications

(75 citation statements)

References 14 publications

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“…A large group of these sources is based on electrical discharge, including owing atmospheric-pressure aerglow (FAPA), 28 direct analysis in real time (DART), 29,30 dielectric barrier discharge ionization (DBDI), 31 and low temperature plasma (LTP). [32][33][34][35] Among these, two promising ADI methods, DESI and DART, have exhibited good performances such as high sensitivity and high selectivity in the analysis of explosives on solid surfaces.…”

Section: -25mentioning

confidence: 99%

Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid, on-site explosives analysis

Chen

Hou

Xiong

et al. 2013

Analyst

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A platform consisting of a halogen lamp, a low temperature plasma (LTP) probe, and a miniature rectilinear ion trap mass spectrometer (RIT-MS) has been constructed and evaluated to detect organic and inorganic explosives on solid surfaces. This platform features two attractive characteristics: high sensitivity for the explosives with low volatility, and rapid analysis speed for the explosives on large surface areas. With non-contact heating by the halogen lamp, the signal intensities for the explosives with relatively high volatility were improved by over an order of magnitude, compared to those obtained at room temperature; and even more, the explosives with low volatility, which could hardly be detected at room temperature, were able to be readily identified. The limits of detection (LODs) of the selected explosives were all at the picogram level (e.g., 10 pg and 20 pg for TNT and RDX, respectively) with a heating time of 3 s. Using manual surface swabbing, the analysis of explosives on a large surface area (7.5 cm Â 2.5 cm) was accomplished within 10 s, and an acceptable sensitivity could be acquired; additionally, inorganic explosives (black powder and firecracker) were successfully detected. Without any sample pretreatment, the platform was used to analyze the wastewater from an explosives factory, confirming the existence of 2,4,6-trinitrotoluene (TNT), 2,4-dinitrotoluene (2,4-DNT), and 2,6-dinitrotoluene (2,6-DNT), and the concentration of TNT was determined to be 5 ng mL À1. All these results indicated that the proposed platform was a promising technique for security monitoring and environmental analysis.

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Section: -25mentioning

confidence: 99%

Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid, on-site explosives analysis

Chen

Hou

Xiong

et al. 2013

Analyst

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“…As an exemple, desorption electrospray ionization (DESI) MS has been successfully applied to several exogenous substances and external uptake detection [17]. Surface assistedlaser desorption/ionization-time-of-flight (SALDI-TOF) MS has been carried out for the detection of some fatty acids, dehydrated cholesterol, squalene, as well as the identification of explosives, drugs, and nicotine residues [8,18,19]. More recently, matrix-assisted-laser desorption/ionization (MALDI) TOF MS has been reported for the detection of endogenous substances, such as amino acids, fatty acids, peptides, dehydrated cholesterol, squalene, DAGs, and TAGs, as well as surfactants, polymers, drugs, pharmaceuticals, and explosives [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Development of Laser Desorption Imaging Mass Spectrometry Methods to Investigate the Molecular Composition of Latent Fingermarks

Lauzon

Dufresne

Chauhan

et al. 2015

J. Am. Soc. Mass Spectrom.

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Abstract. For a century, fingermark analysis has been one of the most important and common methods in forensic investigations. Modern chemical analysis technologies have added the potential to determine the molecular composition of fingermarks and possibly identify chemicals a suspect may have come into contact with. Improvements in analytical detection of the molecular composition of fingermarks is therefore of great importance. In this regard, matrix-assisted laser desorption ionization (MALDI) and laser desorption ionization (LDI) imaging mass spectrometry (IMS) have proven to be useful technologies for fingermark analysis. In these analyses, the choice of ionizing agent and its mode of deposition are critical steps for the identification of molecular markers. Here we propose two novel and complementary IMS approaches for endogenous and exogenous substance detection in fingermarks: sublimation of 2-mercaptobenzothiazol (2-MBT) matrix and silver sputtering.

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“…There is also limited published research regarding suitable methodologies for the extraction, detection, and quantification of peroxide explosives and their precursor chemicals (Crowson and Beardah, 2001;Widmer et al, 2002;Xu et al, 2004;Song-im et al, 2012). Recent advances include methods for the direct detection of peroxide explosives from ambient surfaces without the need for any sample preparation (Cotte-Rodr ıguez et al, 2008;Rowell et al, 2012;Cooks et al, 2006), which is a very useful technique for in situ trace analysis at airports, for example; however, these techniques would not be suitable for wastewater analysis purposes where a cleanup and preconcentration stage would be essential.…”

Section: Introductionmentioning

confidence: 99%

Detection of trace peroxide explosives in environmental samples using solid phase extraction and liquid chromatography mass spectrometry

Gamble

Campos

Morgan

2017

Environmental Forensics

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This article presents solid phase extraction (SPE) and liquid chromatography-mass spectrometry (LC-MS) methods for the trace detection of the peroxide explosives triacetone triperoxide (TATP) and hexamethylene triperoxide diamine (HMTD). Furthermore, experimental studies use these methods to explore the efficiency of wastewater treatment plant (WWTP) processes at removing trace levels of peroxide explosives from water samples to assess the application of the developed methods for the detection of explosives in the environment. The principal results of this study showed that the greatest removal of TATP and HMTD from spiked water samples occurred following the biological treatment stage, however, the WWTP processing did not completely remove all of the analytes from the water, suggesting that such chemicals could contaminate downstream river water samples. The toxicity of chemical pollutants is often determined by their concentration, however, even at trace levels, the monitoring of explosives in the natural environment could be extremely informative for the detection of criminal activity as well as long-term effects upon aquatic life. These findings also have significant implications for crime prevention and disruption approaches that can use this type of data as intelligence to guide investigations regarding the source and attribution of detected explosives.

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Detection of nitro-organic and peroxide explosives in latent fingermarks by DART- and SALDI-TOF-mass spectrometry

Cited by 106 publications

References 14 publications

Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid, on-site explosives analysis

Non-contact halogen lamp heating assisted LTP ionization miniature rectilinear ion trap: a platform for rapid, on-site explosives analysis

Development of Laser Desorption Imaging Mass Spectrometry Methods to Investigate the Molecular Composition of Latent Fingermarks

Detection of trace peroxide explosives in environmental samples using solid phase extraction and liquid chromatography mass spectrometry

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