Detection of novel adenovirus in sick pigeons

Wan, Chunhe; Chen, Cuiteng; Cheng, Longfei; Shi, Shaohua; Fu, Guanghua; Liu, Rongchang; Chen, Hongmei; Fu, Qiuling; Huang, Yu

doi:10.1292/jvms.18-0024

Cited by 10 publications

(6 citation statements)

References 20 publications

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“…During the transportation stops, the practice of joint feeding and watering birds from disparate lofts is a standard procedure and can create ideal conditions for the transmission and long-distance dissemination of various pathogens, especially viruses [ 10 ]. Multiple viruses have been associated and shown to infect pigeons, including those in the families Adenoviridae, Anelloviridae, Circoviridae , Herpesviridae, Paramyxoviruses , Parvoviridae , Picornaviridae and Reoviridae [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

A Pilot Study Investigating the Dynamics of Pigeon Circovirus Recombination in Domesticated Pigeons Housed in a Single Loft

Khalifeh

Kraberger

Dziewulska

et al. 2021

Viruses

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Pigeon circovirus (PiCV) infects pigeon populations worldwide and has been associated with immunosuppression in younger pigeons. Recombination is a common mechanism of evolution that has previously been shown in various members of the Circoviridae family, including PiCV. In this study, three groups of pigeons acquired from separate lofts were screened for PiCV, and their genome sequence was determined. Following this, they were housed in a single loft for 22 days, during which blood and cloacal swab samples were taken. From these blood and cloacal swabs, PiCV genomes were determined with the aim to study the spread and recombination dynamics of PiCV in the birds. Genome sequences of PiCV were determined from seven pigeons (seven tested PiCV positive) before they were housed together in a loft (n = 58 sequences) and thereafter from the ten pigeons from blood and cloacal swabs (n = 120). These 178 PiCV genome sequences represent seven genotypes (98% pairwise identity genotype demarcation), and they share >88% genome-wide pairwise identity. Recombination analysis revealed 13 recombination events, and a recombination hotspot spanning the 3′ prime region, the replication-associated protein (rep) gene and the intergenic region. A cold spot in the capsid protein-coding region of the genome was also identified. The majority of the recombinant regions were identified in the rep coding region. This study provides insights into the evolutionary dynamics of PiCV in pigeons kept under closed rearing systems.

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Section: Introductionmentioning

confidence: 99%

A Pilot Study Investigating the Dynamics of Pigeon Circovirus Recombination in Domesticated Pigeons Housed in a Single Loft

Khalifeh

Kraberger

Dziewulska

et al. 2021

Viruses

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“…Differential diagnoses for infectious and acute liver necrosis in pigeons include C psittaci , adenovirus and herpesvirus 2–5. Although C psittaci is commonly identified within pigeons and therefore of zoonotic concern, actual clinical cases within pigeons are seemingly rare 2.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…Differential diagnoses for infectious and acute liver necrosis in pigeons include C psittaci, adenovirus and herpesvirus. [2][3][4][5] Although C psittaci is commonly identified within pigeons and therefore of zoonotic concern, actual clinical cases within pigeons are seemingly rare. 2 Gross changes would typically include fibrinous air sacculitis and coelomitis, with nonsuppurative, necrotising hepatitis including intracytoplasmic chlamydial organisms identified on histopathology.…”

Section: Differential Diagnosismentioning

confidence: 99%

Rotavirus infection in a racing pigeon (Columba livia) in Great Britain during 2018

Hansen

Stidworthy²,

Jones

et al. 2020

Vet Record Case Reports

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We report the first diagnosis of fatal rotavirus A (RVA) infection in a racing pigeon in Great Britain. In August 2018, a small group of racing pigeons (Columba livia) from one loft exhibited clinical signs of depression, anorexia and vomiting followed by death of two birds despite antimicrobial treatment and fluid therapy. One pigeon, a seven-month-old male, was submitted for postmortem examination. On gross examination, the pigeon was in reasonable body condition with gastrointestinal hyperaemia and green mucoid intestinal content. Histopathology revealed acute hepatocellular degeneration and necrosis with periportal lymphoplasmacytic inflammation in the liver, with ellipsoid hyperplasia and vacuolation in the spleen. Transmission and negative contrast electron microscopy of the liver revealed the presence of a rotavirus. PCR and sequencing confirmed RNA identity of 98.69 per cent with Australian and 100 per cent with German strains of a recently described RVA detected in racing pigeons in 2016 and 2017, respectively.

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“…Adenoviruses are non‐enveloped viruses; their genome consists of a linear double‐stranded DNA molecule ranging from 26 to 45 Kb (Davison, Benko, & Harrach, 2003) encoding 23–50 different polypeptides depending on the species (Wernike et al., 2018). The icosahedral, non‐enveloped capsid of AdVs is composed of three major structural proteins: (a) hexon, (b) fibre protein and (c) penton base (Pacesa et al., 2017; Wan et al., 2018). The hexon gene has hypervariable genomic regions as it encodes one of the major antigens that is involved in the neutralization of the virion (Wernike et al., 2018), but also presents highly conserved regions (Ebner, Pinsker, & Lion, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…The icosahedral, non-enveloped capsid of AdVs is composed of three major structural proteins: (a) hexon, (b) fibre protein and (c) penton base (Pacesa et al, 2017;Wan et al, 2018). The hexon gene has hypervariable genomic regions as it encodes one of the major antigens that is involved in the neutralization of the virion (Wernike et al, 2018), but also presents highly conserved regions (Ebner, Pinsker, & Lion, 2005).…”

Section: Introductionmentioning

confidence: 99%

Adenovirus emergence in a red squirrel (Sciurus vulgaris) in Iberian Peninsula

Côrte‐Real

Lopes

Rebelo

et al. 2020

Transbound. Emerg. Dis.

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Adenoviruses (AdV) are pathogens capable of infecting animals and humans leading to a wide spectrum of diseases. They have a widespread geographical dissemination and infect several species, including red squirrels (Sciurus vulgaris). In the Iberian Peninsula, there are no reports of infection of red squirrels by AdV. In this study, we report for the first time the detection of squirrel AdV in a red squirrel trapped in central Portugal. The phylogenetic analysis showed that the sequences obtained for the hexon and the penton base genes were similar to the Korean squirrel AdV strain and strongly divergent from the strains present in red squirrels in Europe. These findings indicate the emergence of a new strain circulating in Europe and raise concerns regarding the conservation of the red squirrel.

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Detection of novel adenovirus in sick pigeons

Cited by 10 publications

References 20 publications

A Pilot Study Investigating the Dynamics of Pigeon Circovirus Recombination in Domesticated Pigeons Housed in a Single Loft

A Pilot Study Investigating the Dynamics of Pigeon Circovirus Recombination in Domesticated Pigeons Housed in a Single Loft

Rotavirus infection in a racing pigeon (Columba livia) in Great Britain during 2018

Adenovirus emergence in a red squirrel (Sciurus vulgaris) in Iberian Peninsula

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