Detection of Novel Goose Parvovirus Disease Associated with Short Beak and Dwarfism Syndrome in Commercial Ducks

Soliman, Mohamed A.; Erfan, Ahmed M.; Samy, Mohamed; Mahana, Osama; Nasef, Soad A.

doi:10.3390/ani10101833

Cited by 22 publications

(19 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, this is the first report of the coding region in the genome of nGPV isolated from Pekin ducks from outside of Asia; in particular, no sequences are available from Europe. Recently, SBDS was observed in Pekin and mule ducks in Egypt, and infection by nGPV was confirmed with partial sequencing of the vp1 gene [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Short Beak and Dwarfism Syndrome in Ducks in Poland Caused by Novel Goose Parvovirus

Matczuk

Chmielewska-Władyka

Siedlecka

et al. 2020

Animals

View full text Add to dashboard Cite

Short beak and dwarfism syndrome (SBDS), which was previously identified only in mule ducks, is now an emerging disease of Pekin ducks in China and Egypt. The disease is caused by the infection of ducks with a genetic variant of goose parvovirus—novel goose parvovirus (nGPV). In 2019, SBDS was observed for the first time in Poland in eight farms of Pekin ducks. Birds in the affected flock were found to show growth retardation and beak atrophy with tongue protrusions. Morbidity ranged between 15% and 40% (in one flock), while the mortality rate was 4–6%. Co-infection with duck circovirus, a known immunosuppressive agent, was observed in 85.7% of ducks. The complete coding regions of four isolates were sequenced and submitted to GenBank. The phylogenetic analysis revealed a close relationship of Polish viral sequences with the Chinese nGPV. Genomic sequence alignments showed 98.57–99.28% identity with the nGPV sequences obtained in China, and 96.42% identity with the classical GPV (cGPV; Derzsy’s disease). The rate of amino acid mutations in comparison to cGPV and Chinese nGPV was higher in the Rep protein than in the Vp1 protein. To our knowledge, this is the first report of nGPV infection in Pekin ducks in Poland and Europe. It should be emphasized that monitoring and sequencing of waterfowl parvoviruses is important for tracking the viral genetic changes that enable adaptation to new species of waterbirds.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Since 2015, many outbreaks were recorded in Pekin ducks in multiple locations in China, which have caused enormous economic losses due to high morbidity and reduction in the weight and size of the birds [ 3 , 4 , 5 , 6 ]. Furthermore, SBDS was recently observed in Egypt in mule and Pekin ducks [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Short Beak and Dwarfism Syndrome in Ducks in Poland Caused by Novel Goose Parvovirus

Matczuk

Chmielewska-Władyka

Siedlecka

et al. 2020

Animals

View full text Add to dashboard Cite

show abstract

“…While the disease, named short beak and dwarfism syndrome (SBDS), has a reportedly low mortality, the morbidity can be up to 20%. More recently, SBDS has also been observed in Egypt and Poland [ 213 , 214 ].…”

Section: Genus Dependoparvovirusmentioning

confidence: 99%

Small but mighty: old and new parvoviruses of veterinary significance

Jager

Tomlinson

Lopez-Astacio

et al. 2021

Virol J

View full text Add to dashboard Cite

In line with the Latin expression “sed parva forti” meaning “small but mighty,” the family Parvoviridae contains many of the smallest known viruses, some of which result in fatal or debilitating infections. In recent years, advances in metagenomic viral discovery techniques have dramatically increased the identification of novel parvoviruses in both diseased and healthy individuals. While some of these discoveries have solved etiologic mysteries of well-described diseases in animals, many of the newly discovered parvoviruses appear to cause mild or no disease, or disease associations remain to be established. With the increased use of animal parvoviruses as vectors for gene therapy and oncolytic treatments in humans, it becomes all the more important to understand the diversity, pathogenic potential, and evolution of this diverse family of viruses. In this review, we discuss parvoviruses infecting vertebrate animals, with a special focus on pathogens of veterinary significance and viruses discovered within the last four years.

show abstract

“…In 2015, short beak and dwarfism syndrome (SBDS) emerged in Cherry Valley Pekin ducks (a strain of Pekin duck) in China [ 1 , 2 ], thereafter, other breeds of ducks, including mule duck, partridge duck, and sheldrake duck, were also affected [ 3 , 4 ]. In 2019, SBDS emerged in Egypt and Poland, where mule ducks and Cherry Valley Pekin ducks were infected [ 5 , 6 ]. SBDS is a contagious disease of ducks, characterized by growth retardation, short beak, tongue protrusion, lameness, unwillingness to move, and diarrhea [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Reproduction and pathogenesis of short beak and dwarfish syndrome in Cherry Valley Pekin ducks infected with the rescued novel goose parvovirus

Wang

et al. 2022

Virulence

View full text Add to dashboard Cite

Since the outbreak of short beak and dwarfish syndrome (SBDS) in Cherry Valley Pekin ducks in China, novel goose parvovirus (NGPV) has been isolated. Till now, little is known about the NGPV pathogenesis toward Cherry Valley Pekin ducks. Besides, due to detection of duck circovirus co-infection in SBDS clinical cases, whether sole NGPV infection can reproduce all the typical symptoms of SBDS remains unclear. In this study, based on the NGPV isolate SDJN19, an infectious plasmid clone pJNm containing the entire SDJN19 genome was constructed. Transfection of pJNm in embryonated duck eggs resulted in generation of the infectious virus carrying the genetic marker, named rJNm. rJNm infection of 2-day-old Cherry Valley Pekin ducks reproduced all the typical signs of SBDS, including beak atrophy, tongue protrusion, and growth retardation. rJNm can infect Cherry Valley Pekin ducks through the horizontal transmission route, and the infected ducks exhibited the characteristic SBDS symptoms. A high level of serum precipitation antibodies (above 5log 2 ) were induced in the surviving ducks, however, high viral loads were still detected in the duck organs, suggesting persistent NGPV infection in ducks. By incorporating the homologous Rep1 and VP1 gene from classical GPV, two chimeric viruses rJN-cVP1 and rJN-cRep1 were generated. Duck infection tests revealed that the non-structural protein Rep1 played a crucial role in the NGPV pathogenicity. The present result lays a solid foundation for further exploring how the Rep protein contributes to the NGPV pathogenesis.

show abstract

Detection of Novel Goose Parvovirus Disease Associated with Short Beak and Dwarfism Syndrome in Commercial Ducks

Cited by 22 publications

References 43 publications

Short Beak and Dwarfism Syndrome in Ducks in Poland Caused by Novel Goose Parvovirus

Short Beak and Dwarfism Syndrome in Ducks in Poland Caused by Novel Goose Parvovirus

Small but mighty: old and new parvoviruses of veterinary significance

Reproduction and pathogenesis of short beak and dwarfish syndrome in Cherry Valley Pekin ducks infected with the rescued novel goose parvovirus

Contact Info

Product

Resources

About