Detection of oral bacteria in cardiovascular specimens

Abstract

Our results suggest that specific oral bacterial species, such as S. mutans and A. actinomycetemcomitans, are related to bacteremia and may be etiologic factors for the development of cardiovascular diseases.

Roles of Oral Bacteria in Cardiovascular Diseases — From Molecular Mechanisms to Clinical Cases: Cell-Surface Structures of Novel Serotype k Streptococcus mutans Strains and Their Correlation to Virulence

“…We also used a molecular biological method to analyze the distribution of 6 oral streptococcal and 6 periodontopathic species in 203 cardiovascular specimens, including heart valve and atheromatous plaque samples, and S. mutans was detected at the highest frequency (31,32). Analyses of the serotype distribution in all of those S. mutans-positive specimens identified non-c serotypes at a significantly higher frequency as compared with serotype c (33).…”

Oral Surgery in the Human Microbiota Era the role of Periodontal Bacteria

“…The incidence of bacteremia and related systemic diseases due to oral anaerobic bacteria following different procedures such as: endodontic treatment, tooth extraction, periodontal surgery, tongue scraping and root scaling has been well documented [10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] and anaerobe periodontal bacteria are isolated more frequently than facultative anaerobic bacteria, such as Streptococcus spp. [28].…”

Roles of Oral Bacteria in Cardiovascular Diseases — From Molecular Mechanisms to Clinical Cases: Implication of Periodontal Diseases in Development of Systemic Diseases

“…Porphyromonas gingivalis has been reported to be involved in the development of systemic diseases due to systemic inflammation with increased circulating cytokines and mediators, direct infection, and cross-reactivity/molecular mimicry between bacterial antigens and self-antigens (22). Furthermore, periodontal pathogens including P. gingivali s have been detected in heart valve lesions and atheromatous plaque (5,6), amniotic fluid of pregnant women with threatened premature labor (11), and placentas from cases of preterm delivery (12,13). Although a definitive role for P. gingivalis in systemic diseases has yet to be established, the involvement of the bacterium in these disorders has been strongly suggested.…”