Detection of Pathogens in Cerebrospinal Fluid With the BIOFIRE Blood Culture Identification 2 Panel in Two Neonates With Healthcare-associated Central Nervous System Infections

Abstract

the possibility of a metastatic malignancy should be considered. 4 Drainage of the abscess and stabilization of the cervical spine are crucial in these patients. Due to its polymicrobial nature, parenteral administration of broad-spectrum antibiotic therapy against both aerobic and anaerobic microorganisms is essential. MRI provides superior soft tissue evaluation than both ultrasonography and tomography, allowing a more precise differentiation of abscess from cellulitis or lymphadenomegaly. 5 In summary, we present a case of clivus osteomyelitis, a rare complication of RPA, which was successfully treated with prompt medical and surgical intervention. The patient's history of irregular outpatient antibiotic use and the fact that the abscess drainage was performed 2 days after broad-spectrum antibiotic therapy initiation may have contributed to our failure to isolate the causative agent.