Detection of Recurrent Adenoid Cystic Carcinoma With PET-CT

Clinical impact of 18F‐FDG positron emission tomography/CT on adenoid cystic carcinoma of the head and neck

“…These unique pathologic and clinical features mean it is necessary to evaluate the usefulness of 18 F‐FDG PET/CT in patients with ACC of the head and neck (ACCHN) separately from SCC of the head and neck. To our knowledge, the literature contains some case reports, however, few researchers have assessed the clinical impact of 18 F‐FDG PET/CT in patients with ACCHN . Lee et al and Kim et al reported that patients with a high SUVmax had significantly shorter progression‐free survival (PFS) compared with those with a low SUVmax.…”

“…To our knowledge, the literature contains some case reports, however, few researchers have assessed the clinical impact of 18 F-FDG PET/CT in patients with ACCHN. 19,20 Lee et al 18 and Kim et al 21 reported that patients with a high SUVmax had significantly shorter progression-free survival (PFS) compared with those with a low SUVmax. However, SUVmax is measured using the greatest number of pixels in a region of interest, only showing the highest intensity of 18 F-FDG uptake in the tumor, and is unable to reflect the metabolic activity of the whole tumor.…”

Adenoid cystic carcinoma of buccal mucosa: Role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the detection and biopsy of pulmonary metastases and assessment of treatment response

“…[23] Later, various reports demonstrated the role of 18 F-FDG PET/CT in evaluating disease recurrence and identification of distant metastases in ACC, thus affecting patient management. [45] In comparison with magnetic resonance imaging, 18 F-FDG PET/CT showed superior sensitivity for detection of local tumor recurrence and regional and distant metastases. [6] Due to the inherent aggressive nature of the primary neoplasm, distant metastases in most patients is inevitable, even after being treated with curative intent, leading to poor prognosis.…”