Detection of tamarixetin and kaempferide in different tissues by high-performance liquid chromatography in tamarixetin and kaempferide treated rats

Abstract

Tamarixetin and kaempferide were considered as the major active constituents of Tamarix chinensis, and had several known bioactivities. An effective and inexpensive high-performance liquid chromatographic method was established and validated for the determination of tamarixetin and kaempferide in rat tissues following a single oral administration. Tissue distribution showed the highest level of tamarixetin was observed in lung, then in heart; and the highest concentration of kaempferide was determined in heart.