Detection of Undernutrition Among Preschool Children

Abstract

BACKGROUND: Undernutrition among Indian preschool children is very much prevalent and is the predisposing factor for various types of morbidity and mortality. OBJECTIVES: To detect prevalence of under nutrition among preschool children and to find out sensitive tool for detection of under nutrition. Study design: A cross sectional study. Study subjects: Children of age group below 6 years attending anganwadi. Sample size: Total 108 children attending anganwadi were included in the study. Data collection: Data was recorded in prestructured proforma, consisting information regarding personal data and anthropometric measurements like height, weight, head circumference, mid arm circumference etc. RESULTS: The overall prevalence of undernutrition according to weight for height, body mass index, weight for age by IAP classification and by Kanawati and Mc Laren index was 36.11%, 41.67%, 42.59% and 66.67%, respectively. Most sensitive tool observed was Kanawati and Mc Laren index to detect true positive undernutrition cases. CONCLUSION: Maximum number of undernutrition cases were detected by Kanawati and Mc Laren index, whose ability of detecting true undernutrition cases is very much high in comparison with other indices, even though the sensitivity to detect normal children and predictive ability is less. So the Kanawati and Mc Laren index is considered superior to detect undernutrition in the community.

An assessment of the validity of the nutritional indices among under-fives in the catchment area of rural health and training center of a teaching institute in Bareilly

“…In the study on detection of undernutrition among preschool children by Raje et al .,[11] 66.67% children were suffering from malnutrition according to Kanawati and McLaren index which was found to be 74.2% and 48.3% according to it, respectively, in our study. The same study stated that according to IAP and Rao index 42.59% and 41.67% children were malnourished, which is comparable with 48.2% and 33.1% found in our study.…”

A family of structural and functional models for the active site of a unique dioxygenase: Acireductone dioxygenase (ARD)

“…Although LiACAC's symmetry does not allow for testing the regioselective chemistry observed in ARD, it has been used in the study of analogous model systems as a model compound for testing oxidative reactivity. [20][21][22] Furthermore, this substrate is biologically relevant to other related oxygenases specifically acetylacetone dioxygenase (Dke1). 29 In a typical oxygenation reaction, a 0.035 M solution of the nickel complex in deuterated methanol was mixed in a 1:5 ratio with LiACAC in a dynamic atmosphere of oxygen and heated to 35°C while monitored for changes via 1 H-NMR of the reaction mixture.…”

“…This current proof of principle study opens the door to suggest role that ligand environment might play in these substrate activations, but it also highlights the need for further studies that test the influence of ligand environments analogous to the enzyme and their influence on oxidative reactivity. 18,19,20 and probing the influence of ligand donating abilities on reactivity. These advances will contribute more directly to the debate over how the metal, substrate coordination, and electronic structure of the enzyme's active site impact the unique regioselectivity of ARD.…”

“…Recent work with macrocyclic N4 tetradentate ligands (N,N '-di-benzyl-2,11-diaza[3,3] (2,6)pyridinophane), and their corresponding Ni(II) complexes, reported the oxidative cleavage of an ARD substrate analogue under atmospheric oxygen and ambient conditions. 20 Although these are functional models, the N4 systems lack all of the structural and electronic characteristics to accurately mimic the electronic environment of ARD's active site, specifically the introduction of the oxygen moiety corresponding to the glutamate donor in ARD. It is important to note that additional work reported the use of an N3 chelating ligand (2,6-bis(1-methylbenzimidazolyl)pyridine) to make Ni(II) complexes that were shown to be reactive with substituted diketones towards C-C oxidative bond cleavage analogous to the enzymatic reactivity.…”