2022
DOI: 10.21608/ejmm.2022.251053
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Detection of vacA, cagA and iceA genes of H. pylori in dyspeptic patients and their association with clinical data and histopathological abnormalities

Abstract: Background: Despite that most H. pylori infections are asymptomatic, some can develop major diseases like peptic ulcer and adenocarcinoma of stomach. Objectives: This study aimed to study the prevalence of H. pylori using real time PCR. Furthermore, detection of the cagA, iceA1, iceA2, vacA virulence genes and their relationship to clinical and histopathological alterations. Methods: Two gastric specimens were taken from every patient endoscopically, one of them was sent to histopathological analysis and the s… Show more

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“…The CagA seroprevalence rate reached 27.9% among dyspeptic patients. Our results converge with the results of studies conducted in Saudi Arabia [18], Egypt [19], and Turkey [20].…”
Section: Discussionsupporting
confidence: 91%
“…The CagA seroprevalence rate reached 27.9% among dyspeptic patients. Our results converge with the results of studies conducted in Saudi Arabia [18], Egypt [19], and Turkey [20].…”
Section: Discussionsupporting
confidence: 91%