Detection rate of prostate cancer on biopsy according to serum prostate-specific antigen in Korean men: A multicenter study

Yang, Won Jae; Lee, Dong Hoon; Chung, Byung Ha; Cho, Jin Seon; Choi, Young Deuk; Kim, Sejoong; Cho, In Rae; Kim, Hong Sup; Kim, Chun Il; Hong, Sung Joon

doi:10.1016/j.urology.2005.08.027

Cited by 35 publications

(22 citation statements)

References 12 publications

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“…The detection rate in patients with PSA levels between 4 and 10 ng/ml was 11.8%, which is slightly lower than the 15.8% rate reported in Japanese and Korean men [3,7] , and much lower than the 25-35% rate reported in American men [8][9][10][11] . In patients with PSA levels more than 10 ng/ml also, our detection rate of 40% is lower than the 59.5% rate reported in Korean and Japanese men, and the 67% rate reported in American men [3,11] . The reason for a lower incidence of prostate cancer in Kuwaiti men has been suggested to be due to low circulating androgens and their adrenal precursors when compared to Caucasians [12] .…”

Section: Discussioncontrasting

confidence: 57%

Detection Rate and Clinical Pattern of Prostate Cancer in Kuwait: A Single-Center Experience

Arun

Abul²,

Mathew

2010

Med Princ Pract

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Objective: To determine the detection rate and clinical pattern of prostate cancer in Kuwait. Subjects and Methods: One hundred and fifty-three males suspected of having prostate cancer based on elevation of prostate-specific antigen (PSA) of more than 4 ng/ml underwent transrectal-ultrasound (TRUS)-guided needle biopsy of the prostate between January 2003 and January 2008; these formed the study group. Analysis of prostate cancer was based on age, prostate volume, PSA level and on finding any abnormality based on a combination of the diagnostic tools. Results: A diagnosis of prostate cancer was histologically confirmed in 42 (27.4%) patients. In those aged <55, 56–65, 66–75 and >76 years, the detection rates were 16.7, 17.6, 33.3 and 40.7%, respectively. In those with prostate volumes of >71, 51–70, 31–50 and <30 g, the detection rates were 18.2, 23.8, 30.8 and 42.9%, respectively. When the PSA levels were divided into groups of 4–10, 10–20, 20–100 and >100 ng/ml, the cancer detection rate was 11.8, 20.5, 47.1 and 83.3%, respectively. When 1, 2 and 3 of the 3 diagnostic tools (digital rectal examination, PSA, TRUS) were abnormal, the detection rate was 15.6, 27.9 and 80%, respectively. Conclusions: Our data showed that the prostate cancer rate differs according to the region and that the rate was low in our center. Higher PSA and higher number of diagnostic tools with abnormal findings were associated with a higher incidence of prostate cancer.

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Section: Discussioncontrasting

confidence: 57%

Detection Rate and Clinical Pattern of Prostate Cancer in Kuwait: A Single-Center Experience

Arun

Abul²,

Mathew

2010

Med Princ Pract

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“…The detection rate of prostate cancer in the Asian population is lower than that in American men [3][4][5][6]. In two studies on Korean men, the cancer detection rate for the PSA subgroup between 4 and 10 ng/ml was 13.8% and 15.9%, [4,5] similar to the 15.8% rate in Japanese men reported by Egawa et al [6].…”

Section: Discussionsupporting

confidence: 53%

“…In Western countries, the probability of cancer is around 25% if serum PSA is between 4.1 and 10 ng/ml, and it is estimated that the probability of cancer is greater than 30% when serum PSA is higher than 10 ng/ml [1,2]. The detection rate of prostate cancer in the Asian population is lower than that in American men [3][4][5][6]. In two studies on Korean men, the cancer detection rate for the PSA subgroup between 4 and 10 ng/ml was 13.8% and 15.9%, [4,5] similar to the 15.8% rate in Japanese men reported by Egawa et al [6].…”

Section: Discussionmentioning

confidence: 99%

Prostate biopsy in subjects with abnormal transrectal ultrasonography but normal digital examination findings and prostate-specific antigen levels

et al. 2007

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“…The possible reason may be due to the ethnic difference in the detection rates of prostate cancer. However, when comparing the detection rate with that of Korean men with similar ethnicity of Chinese men in the study by Yang et al in 2006, our data showed that the cancer detection rate was higher than that in his study (42.8 vs. 39.7%) [18]. The similar result was also observed when comparing our results with that in another study of Korean men by Seo et al in 2007 (42.8 vs. 32.7%) [19].…”

Section: Discussionmentioning

confidence: 57%

Detection rate of prostate cancer following biopsy among the northern Han Chinese population: a single-center retrospective study of 1022 cases

et al. 2017

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BackgroundProstate cancer is known to have ethnic and regional differences. The study aimed to clinically evaluate the detection rate of prostate cancer on transrectal ultrasonography (TRUS)-guided prostate biopsy and analyze its characteristics among the northern Han Chinese population at a single center.MethodsBetween October 2009 and September 2016, a total of 1027 Chinese men, who had undergone TRUS-guided prostate biopsy at Qingdao Municipal Hospital, were retrospectively analyzed. Prostate biopsies were performed in the case of an abnormally elevated serum PSA level, and/or abnormal digital rectal examination (DRE) findings, and/or suspicious prostatic imaging findings.ResultsOf the 1022 men enrolled in the analysis, 438 patients (42.8%) were diagnosed with prostate adenocarcinoma histologically. When serum PSA levels were divided into five subgroups (less than 4.0, 4.0 to 10.0, 10.0 to 20.0, 20.0 to 100.0, and ≥ 100.0 ng/ml), the detection rates of prostate cancer were 12.4, 15.9, 34.1, 66.2, and 93.8%, respectively. With serum PSA levels of 4.0 to 10.0 ng/ml, the cancer detection rates for a normal DRE and a suspect DRE finding were 13.5 and 58.2%, respectively. Accordingly, the cancer detection rates for a normal imaging and a suspect imaging finding were 13.5 and 58.2%, respectively. Besides, a large proportion of the patients were in the clinically advanced stage.ConclusionsThe present study data reported a relatively higher prostate cancer detection rate of 42.8% and that the majority of the patients presented with clinically advanced prostate cancers within a local clinical urologic practice. An early detection and screening program for prostate cancer is of great need to reduce the burden from this disease among the northern Han Chinese population.

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Detection rate of prostate cancer on biopsy according to serum prostate-specific antigen in Korean men: A multicenter study

Cited by 35 publications

References 12 publications

Detection Rate and Clinical Pattern of Prostate Cancer in Kuwait: A Single-Center Experience

Detection Rate and Clinical Pattern of Prostate Cancer in Kuwait: A Single-Center Experience

Prostate biopsy in subjects with abnormal transrectal ultrasonography but normal digital examination findings and prostate-specific antigen levels

Detection rate of prostate cancer following biopsy among the northern Han Chinese population: a single-center retrospective study of 1022 cases

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