Landslides pose a significant threat worldwide, leading to numerous fatalities and severe economic losses. The city of Manizales, located in the Colombian Andes, is particularly vulnerable due to its steep topography and permeable volcanic ash-derived soils. This study aims to assess landslide hazards in Manizales by integrating shallow planar and deep-seated circular failure mechanisms using physics-based models (TRIGRS and Scoops3D). By combining hazard zonation maps with rainfall thresholds calibrated through historical data, we provide a refined approach for early warning systems (EWS) in the region. Our results underscore the significance of the landslide hazard maps, which combine shallow planar and deep-seated circular failure scenarios. By categorizing urban areas into high, medium, and low-risk zones, we offer a practical framework for urban planning. Moreover, we developed physics-based rainfall thresholds for early landslide warning, simplifying their application while aiming to enhance regional predictive accuracy. This comprehensive approach equips local authorities with essential tools to mitigate landslide risks, refine hazard zoning, and strengthen early warning systems, promoting safer urban development in the Andean region and beyond, as the physics-based methods used are well-established and implemented globally.