Determinación de la dosis eritemática mínima y reacciones anómalas a radiación ultravioleta A según fototipo

Ferriols, Amparo Pérez; Aguilera, José; Aguilera, Paula; Argila, D. de; Barnadas, M.A.; Cabo, Xavier; Carrrascosa, J.M.; Aranda, María Victoria de Gálvez; Gardeazábal, Jesús; Giménez-Arnau, A.M.; Lecha, M.; Lorente, J.; Martínez‐Lozano, J. A.; Granados, Mónica; Solá, Yolanda; Utrillas, M. P.

doi:10.1016/j.ad.2014.05.001

Cited by 26 publications

(3 citation statements)

References 12 publications

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“…It is important to highlight that the spectral irradiance of the UV lamp is 31 AE 4 Wm À2 , which is lower than the solar spectral irradiance measured at solar noon (37 AE 4 Wm À2 ) during the spring period [14]. Moreover, the dose of UV-A radiation used in this work was 14.88 J/cm 2 while the normal minimal erythema dose is greater than 20 J/cm 2 [19,20]. Therefore, the UV-A dose applied in this study would be considered safe for clinical therapy.…”

Section: Steady-state Irradiationmentioning

confidence: 78%

Synergistic effect of carboxypterin and methylene blue applied to antimicrobial photodynamic therapy against mature biofilm of Klebsiella pneumoniae

Tosato

Schilardi

Mele

et al. 2020

Heliyon

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The control of multidrug-resistant (MDR) bacteria is a growing public health problem, and new strategies are urgently needed for the control of the infections caused by these microorganisms. Notoriously, some MDR microorganisms generate complex structures or biofilms, which adhere to surfaces and confer extraordinary resistance properties that are fundamental challenges to control infections. One of the promising strategies for the control of MDR bacteria is antimicrobial photodynamic therapy (aPDT), which takes advantage of suitable photosensitizers (PS), oxygen and radiation to eradicate microorganisms by the generation of highly reactive species, including reactive oxygen species (ROS) that cause cytotoxic damage and cell death. Habitual aPDT treatments use only methylene blue (MB), but MDR microorganism eradication is not completely achieved. The key result of this study revealed that a combination of two known PSs, 6-carboxypterin (Cap, 100 μM) and MB (2.5-10 μM) exposed to ultraviolet and visible radiation, presents a synergistic effect on the eradication of a MDR Klebsiella pneumoniae strain. Similar effect was observed when the treatment was performed either with planktonic or biofilm growing cells. Moreover, it was found that after treatment the killing action continues in the absence of irradiation leading to the eradication of the microorganisms growing in biofilm. Therefore, the combined aPDT represents a promising strategy for the management of clinical contact surfaces, disinfection of surgical instruments, biofouling and even antimicrobial wastewater treatment.

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Section: Steady-state Irradiationmentioning

confidence: 78%

Synergistic effect of carboxypterin and methylene blue applied to antimicrobial photodynamic therapy against mature biofilm of Klebsiella pneumoniae

Tosato

Schilardi

Mele

et al. 2020

Heliyon

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show abstract

“…After 24 h, his minimal erythematous dose (MED) for UVB was inferior to 7.4 mJ/cm 2 (normal MED for Skin Type IV-V: 51 ± 6 mJ/cm 2 ). 3 Papule formation was induced by UVB doses greater than 33.3 mJ/cm 2 . Additionally, pathological response to UVA at doses of 5, 10 and 15 J/cm 2 was observed (Figure 2A).…”

Section: Systemic Photosensitivity Due To Levetiracetam: Report Of a ...mentioning

confidence: 99%

“…A phototest revealed a MED for UVB inferior to 7.4 mJ/cm 2 (blue arrows indicate from left to right erythematous response to doses of 4.9, 7.4, 10, 13.5, 18.3, 24.7, 33.3 and 45 mJ/ cm 2 , respectively) after 24 h, much under the physiological range for his Fitzpatrick skin type (51 ± 6 mJ/cm 2 for a skin type IV, also applicable to the patient's skin type V). 3 In addition, pathological response to UVA at doses of 5, 10 and 15 J/cm 2 | 293…”

Section: Data Ava I L a B I L I T Y S Tat E M E N Tmentioning

confidence: 99%

Systemic photosensitivity due to levetiracetam: Report of a previously undescribed adverse effect

Bonino

Pérez-Feal

Rodiño³

et al. 2022

Photoderm Photoimm Photomed

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Phototherapy in Atopic Dermatitis

Salvador

Pérez‐Ferriols

2017

Advances in Experimental Medicine and Biology

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Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. Currently management of AD includes avoidance of triggering factors, skin care aiming to compensate the skin barrier defects, anti-inflammatory therapy (mostly topical corticosteroids and topical calcineurin inhibitors). When these first-line approaches are unsuccessful, systemic treatment or phototherapy ought to be carried out as next line of defence. Current phototherapy modalities for AD include broadband UVB (290-320 nm), narrowband UVB (311-313 nm), UVA-1 therapy (340-400 nm), UVA therapy plus 8-methoxypsoralens (PUVA), 308 nm excimer laser (EL) and Full spectrum light (FSL).

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Determinación de la dosis eritemática mínima y reacciones anómalas a radiación ultravioleta A según fototipo

Cited by 26 publications

References 12 publications

Synergistic effect of carboxypterin and methylene blue applied to antimicrobial photodynamic therapy against mature biofilm of Klebsiella pneumoniae

Synergistic effect of carboxypterin and methylene blue applied to antimicrobial photodynamic therapy against mature biofilm of Klebsiella pneumoniae

Systemic photosensitivity due to levetiracetam: Report of a previously undescribed adverse effect

Phototherapy in Atopic Dermatitis

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