In this volatile world where sustainability is a major concern, the growing importance of the backbone of the economies, the financial sector, is inevitable. This chapter tries to seek the factors responsible for the changes in the financial performance of the commercial banks in Indian banking sector. The secondary data related to selected key performance indicators (KPI) are selected for the top ten banks for the years 2018-19 to 2022-23. These also include the ESG risk rating of these banks that gives an idea of the overall performance of the banks in the long run. The chapter further tries to forecast a trend of the selected KPIs. The results of the exploratory factor analysis followed by dependency tests proved that there is considerable impact of net non-performing assets, current account savings account, and the ratio of fixed assets to total assets on profitability of the banks.