Coronavirus is a public health issue with socioeconomic and livelihood dimensions. The World Health Organization declared the current novel coronavirus disease (COVID-19) epidemic a public health emergency of international concern on January 30, 2020, and a global pandemic on March 11, 2020. The South African government has implemented different strategies, ranging from total lockdown in certain locations and provision of palliatives in some provinces across the country. This study, therefore, investigated the correlates of vulnerability and responsiveness to the adverse impacts of COVID-19 in South Africa. The study utilized primary data collected among 477 respondents. Descriptive statistical tools, Tobit and Probit regression models, were used to analyze the data. The study found different levels of vulnerability (low, medium, and high) and responsiveness among households, including stocking up of food items, remote working, reliance on palliatives, and social grant provision, among others. Some of the correlates of responsiveness to the COVID-19 pandemic include being employed, the type of community, and the income of respondents. The study, therefore, recommends increased investments in welfare programmes (safety nets, palliative measures and economic stimulus packages) as well as capacity building of households through education to reduce vulnerability. Doi: 10.28991/HIJ-2022-03-04-02 Full Text: PDF