Déterminants du neuropaludisme en milieu pédiatrique congolais

Ossou-Nguiet, P.M.; Okoko, A.R.; Bowassa, G. Ekouya; Oko, A.P.; Mabiala-Babela, J. R.; Mamadoud, I.C. Ndjobo; Moyen, G.

doi:10.1016/j.neurol.2012.11.003

Cited by 9 publications

(7 citation statements)

References 16 publications

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“…Of these, nine articles were identified with information on the incidence or the prevalence of malaria parasite infection (Table 2) [9, 11–18]. Most of these studies were performed in children aged ≤15 years.…”

Section: Resultsmentioning

confidence: 99%

“…A total of 1135 children were enrolled in this study and 34.9% (396) of them were diagnosed as severe malaria cases. Among them, 35.9% were further classified as coma cases, while 23.5, 20.8, 10.3, 7.4 and 3.6% were found to experience convulsions, coma and anaemia, prostration, convulsions and anaemia, and convulsions and respiratory distress, respectively [18]. …”

Section: Resultsmentioning

confidence: 99%

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Malaria epidemiological research in the Republic of Congo

Koukouikila-Koussounda

Ntoumi

2016

Malar J

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BackgroundReliable and comprehensive information on the burden of malaria is critical for guiding national and international efforts in malaria control. The purpose of this review is to provide an overview of published data and available information on malaria resulting from field studies/investigations conducted in the Republic of Congo (RoC) from 1992 to 2015, as baseline for assisting public health authorities and researchers to define future research priorities as well as interventions.MethodsThis review considers data from peer-reviewed articles and information from the National Malaria Control Programme reports, based on field investigations or samples collected from 1992 to 2015. Peer-reviewed papers were searched throughout online bibliographic databases PubMed, HINARI and Google Scholar using the following terms: “malaria”, “Congo”, “Brazzaville”, “prevalence”, “antimalarial”, “efficacy”, “falciparum”, “genetic”, “diversity”. Original articles and reviews were included and selection of relevant papers was made.ResultsTwenty-eight published articles were included in this review and two additional records from the National Malaria Control Programme were also considered. The majority of studies were conducted in Brazzaville and Pointe-Noire.ConclusionThe present systematic review reveals that number of studies have been conducted in the RoC with regard to malaria. However, their results cannot formally be generalized at the country level. This suggests a need for implementing regular multisite investigations and surveys that may be representative of the country, calling for the support and lead of the Ministry of Health.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Malaria epidemiological research in the Republic of Congo

Koukouikila-Koussounda

Ntoumi

2016

Malar J

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“…Findings on the relationship between delay in receiving appropriate treatment for uncomplicated malaria (UM) and risk of developing severe disease are not consistent across all studies [20]. Several studies in both African and non-African settings have reported an increased risk of SM with delay [21][22][23][24][25][26][27][28]. By contrast, some studies found no difference in duration of symptoms between severe and uncomplicated disease [29][30][31][32], but singlesite studies of SM frequently suffer from small case denominators and reduction of statistical power in analyses stratified by SM phenotype.…”

Section: Introductionmentioning

confidence: 99%

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

et al. 2020

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“…Le paludisme avait été l'affection la plus fréquente après les causes néonatales. Sa fréquence intra-hospitalière élevée a été notée dans plusieurs travaux [10,13,14]. Nos résultats montrent que près d'un cas de paludisme sur deux s'était présenté sous une forme grave.…”

Section: Analyse Des Donnéesunclassified

“…Nos résultats montrent que près d'un cas de paludisme sur deux s'était présenté sous une forme grave. En revanche dans d'autres études africaines, la fréquence des cas graves était plus faible notamment au Congo [14] et au Gabon [15]. La fréquence élevée de formes graves dans notre structure s'explique par le fait qu'elle a un statut de référence recevant les cas les plus graves.…”

Section: Analyse Des Donnéesunclassified