Determinants of behavioral and psychological symptoms of dementia: A scoping review of the evidence

Kolanowski, Ann; Boltz, Marie; Galik, Elizabeth; Gitlin, Laura N.; Kales, Helen C.; Resnick, Barbara; Haitsma, Kimberly S. Van; Knehans, Amy; Sutterlin, Jane; Sefcik, Justine S.; Liu, Wen; Petrovsky, Darina; Massimo, Lauren; Gilmore‐Bykovskyi, Andrea; MacAndrew, Margaret; Brewster, Glenna; Nalls, Vycki; Jao, Ying Ling; Duffort, Naomi; Scerpella, Danny

doi:10.1016/j.outlook.2017.06.006

Cited by 123 publications

(118 citation statements)

References 96 publications

Supporting

Mentioning

115

Contrasting

Unclassified

Order By: Relevance

“…The theory of caritative leadership informs both administrative and practical operations in such a way that caregivers can develop and prevent patients’ suffering (Bondas, ). Effective intervention is necessary to prevent aggressive behaviour and reduce caregivers burden (Kolanowski et al., ).…”

Section: Discussionmentioning

confidence: 99%

Caregivers’ perceptions of aggressive behaviour in nursing home residents living with dementia: A meta‐ethnography

Nybakken

Strandås

Bondas

2018

Journal of Advanced Nursing

View full text Add to dashboard Cite

Caregivers perceive and interpret aggressive behaviour related to the resident's illness and person, the caregiver's attitude and approach, or a demanding environment. Further research and theoretical development is important, as shown by different perceptions and interpretations, as well as central definitions in research publications. The study informs evidence-based practice and health-policy by showing the importance of developing reflective relational nursing care, knowledge, and competence in nursing homes.

show abstract

Section: Discussionmentioning

confidence: 99%

Caregivers’ perceptions of aggressive behaviour in nursing home residents living with dementia: A meta‐ethnography

Nybakken

Strandås

Bondas

2018

Journal of Advanced Nursing

View full text Add to dashboard Cite

show abstract

“…pituitary adenomas release excess ACTH thereby chronically elevating circulating Cort, resulting in Cushing's disease; Boscaro et al, 2001 ). The recent extensive dissection of the neural circuitry that mediates behavioral and hormonal stress responses has uncovered a plethora of brain regions in which disease-associated dysfunction can produce neuropsychiatric symptoms, particularly in the context of neurodegeneration ( Kolanowski et al, 2017 ; Ross et al, 2017 ).…”

Section: The Relationship Between Stress and Neurodegenerative Diseasmentioning

confidence: 99%

The relationship between stress and Alzheimer's disease

Justice

2018

Neurobiology of Stress

184

119

View full text Add to dashboard Cite

Stress is critically involved in the development and progression of disease. From the stress of undergoing treatments to facing your own mortality, the physiological processes that stress drives have a serious detrimental effect on the ability to heal, cope and maintain a positive quality of life. This is becoming increasingly clear in the case of neurodegenerative diseases. Neurodegenerative diseases involve the devastating loss of cognitive and motor function which is stressful in itself, but can also disrupt neural circuits that mediate stress responses. Disrupting these circuits produces aberrant emotional and aggressive behavior that causes long-term care to be especially difficult. In addition, added stress drives progression of the disease and can exacerbate symptoms. In this review, I describe how neural and endocrine pathways activated by stress interact with ongoing neurodegenerative disease from both a clinical and experimental perspective.

show abstract

“…These symptoms form clusters and four NPS subsyndromes: hyperactivity, psychosis, affective symptoms, and apathy, have been identified [8]. NPS have been associated with severity of cognitive impairments and declining functional abilities [9]. Several studies have also shown that having NPS impairs quality of life [10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Severity of both neuropsychiatric symptoms and dementia is associated with quality of life in nursing home residents

et al. 2019

View full text Add to dashboard Cite

The aim was to investigate the association of severity of neuropsychiatric symptoms and health-related quality of life and their interaction with dementia severity among institutionalized older people with dementia. Findings Neuropsychiatric symptom burden was associated with higher health-related quality of life in residents with severe dementia, whereas among those residents with mild-moderate dementia this association was not seen. Very low functional capacity was linked to both low number of neuropsychiatric symptoms and low health-related quality of life among those with severe dementia. Message In severe dementia, higher neuropsychiatric symptom burden and better health-related quality of life indicate better functioning and higher vitality.

show abstract

Determinants of behavioral and psychological symptoms of dementia: A scoping review of the evidence

Abstract: Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.

Cited by 123 publications

References 96 publications

Caregivers’ perceptions of aggressive behaviour in nursing home residents living with dementia: A meta‐ethnography

Caregivers’ perceptions of aggressive behaviour in nursing home residents living with dementia: A meta‐ethnography

The relationship between stress and Alzheimer's disease

Severity of both neuropsychiatric symptoms and dementia is associated with quality of life in nursing home residents

Contact Info

Product

Resources

About