Determinants of bone mineral content in childhood

Trouerbach, W. T.; Man, Stella A. de; Gommers, Diederik; Zwamborn, A. W.; Grobbee, Diederick E.

doi:10.1016/0169-6009(91)90050-a

Cited by 29 publications

(10 citation statements)

References 15 publications

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“…This close relationship between bone mass and anthropometric variables had already been identified in early studies by Mazess and Cameron (22) and was later confirmed in studies performed on bone from the appendicular bone structures (19,(23)(24)(25)(26)(27)(28) and from the lumbar spine (10,11,15,16,29,30).…”

Section: Discussionmentioning

confidence: 56%

Bone mineral density of the lumbar spine of Brazilian children and adolescents aged 6 to 14 years

Fonseca

Szejnfeld

Terreri

et al. 2001

Braz J Med Biol Res

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The authors performed a study of bone mass in eutrophic Brazilian children and adolescents using dual-energy X-ray absorptiometry (DXA) in order to obtain curves for bone mineral content (BMC) and bone mineral density (BMD) by chronological age and correlate these values with weight and height. Healthy Caucasian children and adolescents, 120 boys and 135 girls, 6 to 14 years of age, residents of São Paulo, Brazil, were selected from the Pediatric Department outpatient clinic of Hospital São Paulo (Universidade Federal de São Paulo). BMC, BMD and the area of the vertebral body of the L2-L4 segment were obtained by DXA. BMC and BMD for the lumbar spine (L2-L4) presented a progressive increase between 6 and 14 years of age in both sexes, with a distribution that fitted an exponential curve. We identified an increase of mineral content in female patients older than 11 years which was maintained until 13 years of age, when a new decrease in the velocity of bone mineralization occurred. Male patients presented a period of accelerated bone mass gain after 11 years of age that was maintained until 14 years of age. At 14 years of age the mean BMD values for boys and girls were 0.984 and 1.017 g/cm 2 , respectively. A stepwise multiple regression analysis of paired variables showed that the vertebral area-age pair was the most significant in the determination of BMD values and the introduction of a third variable (weight or height) did not significantly increase the correlation coefficient.

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Section: Discussionmentioning

confidence: 56%

Bone mineral density of the lumbar spine of Brazilian children and adolescents aged 6 to 14 years

Fonseca

Szejnfeld

Terreri

et al. 2001

Braz J Med Biol Res

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“…Similar results have been obtained by quantitative roentgen microdensitometry [21], single photon absortiometry [6] and by DEXA [4]. However, in all circumstances the so called BD values were obtained by dividing BMC for the projected area (areal BD, mg/cm 2) which is still dependent upon bone dimensions.…”

Section: Discussionmentioning

confidence: 67%

Evaluation of cortical thickness and bone density by roentgen microdensitometry in growing males and females

et al. 1996

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“…Consequently, the BMD as a ‘true’ volumetric density can be determined. With this technique two measurement sites (region of interest; ROI) are used, the first ROI is at the mid‐point of the line between the distal and proximal edge of the phalanx (BMD 50% ) consisting mainly of cortical bone (approximately 80%), the second ROI is located at the proximal quarter‐point of this line (BMD 25% ), consisting mainly of trabecular bone (approximately 60%) (Trouerbach et al ., 1991). This technique has a short‐term in vivo coefficient of variance of less than 1%, being slightly better than precision figures for the other RA techniques (Yates et al ., 1995; Ravn et al ., 1996).…”

Section: Methodsmentioning

confidence: 81%

A longitudinal study on bone mineral density until adulthood in girls with Turner's syndrome participating in a growth hormone injection frequency‐response trial

Sas

Keizer-Schrama

Stijnen

et al. 2000

Clinical Endocrinology

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Most untreated girls with Turner syndrome, age >/= 11 years, have a normal volumetric BMD of the cortical, as well as of the trabecular bone compared to healthy girls. During GH treatment with 6 IU/m2/day in combination with low dose oestrogens, the BMD SDS increases significantly. After discontinuation of GH treatment and the use of oestrogens in an adult dosage, the BMD was as high as in young healthy women.

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Determinants of bone mineral content in childhood

Cited by 29 publications

References 15 publications

Bone mineral density of the lumbar spine of Brazilian children and adolescents aged 6 to 14 years

Bone mineral density of the lumbar spine of Brazilian children and adolescents aged 6 to 14 years

Evaluation of cortical thickness and bone density by roentgen microdensitometry in growing males and females

A longitudinal study on bone mineral density until adulthood in girls with Turner's syndrome participating in a growth hormone injection frequency‐response trial

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