Determinants of depression among people with epilepsy in Central Ethiopia

Abstract

BackgroundDepression is the most frequently and highly occurring mental disorders in epilepsy patients. When depression is comorbid with epilepsy, it leads to low employment and poor quality of life. Thus, the aim of this study was to assess the prevalence and associated factors of depression among people living with epilepsy in Central Ethiopia.MethodsInstitution-based cross-sectional study was conducted from April to May 2015 at Amanuel Mental Specialized and TikurAnbesa Hospitals, Addis Ababa, Ethiopia. Samples of 422 epilepsy patients were selected, and data on depression were collected using validated questionnaire using face-to-face interview technique. Logistic regression analysis was performed to assess predictors of depression.ResultsThe study indicated that the prevalence of depression among people with epilepsy was 43.8%. Factors associated with depression were being female (AOR 2.48; 95% CI, 1.61.3.81), being single (AOR 2.23; 95% CI 1.38–3.60), perceived stigma (AOR 2.47; 95% CI 1.59–3.83), medication adherence (AOR 2.85; 95% CI 1.64–4.96), and current substance use (AOR 2.10; 95% CI 1.34–3.30).ConclusionThere is a high prevalence of depression among epilepsy patients. Early detection and prompt management of depressive symptoms are critically important in reducing depression burden among people living with epilepsy.

Perceived Stigma in Epilepsy Patients in a Low Income Country; Ethiopia: A Review and Meta-Analysis of the Prevalence and Related Factors.

“…Our screening for eligible articles resulted in 10 studies (20,(26)(27)(28)(29)(30)(31)(32)(33)(34), that assessed perceived stigma AND/OR the associated factors among 4016 people with epilepsy in the context of Ethiopia. All of the 10 studies were cross-sectional studies published between 2009 and 2018.…”

“…All of the 10 studies were cross-sectional studies published between 2009 and 2018. Of these studies, three were conducted in Addis Ababa (28,29,32); the capital city of Ethiopia, another three were from Oromia regional state (20,33,34), two from Amhara regional state (27,30) and the remaining two from southern Ethiopia (SNNP) (26,31).…”

“…Considering the measurement tool, one study used Jacoby stigma scale (32), two studies used modi ed Family Interview Schedule (FIS) (20,27), another two used three-item stigma scales (28,34), and four utilized Kili stigma scale (29)(30)(31)33) to measure perceived stigma in people with epilepsy. However, the assessment tool was not speci ed in one of the included studies.…”

“…However, the assessment tool was not speci ed in one of the included studies. Among studies included; three (20,26,28) have no report regarding the response rate of the study participants. Eight of the included studies (27-34) used a systematic sampling technique and one study implemented a simple random sampling (26) and no sampling technique was reported in the remaining one study(20) ( Table 1).…”

“…Overall the quality score of the 10 included studies ranges from 6 (26) to 10 (27). There of the included studies (26,29,33) had moderate quality, and the remaining six of the included studies (20,27,28,(30)(31)(32)34) had a good quality score. A study with poor quality was not present in this study (Additional le 1).…”