Determinants of G Protein Inhibition of Presynaptic Calcium Channels

Overview of Voltage‐gated Calcium Channels

“…The literature on calcium channel modulation is vast, and here we briefly discuss only some of the major regulatory pathways. For a more detailed overview of calcium channel modulation, refer to Bannister et al [92], Nirdosh and Zamponi [93], and Lee and Catterall [94]. Gbg binds to the I-II linker to inhibit current in some channel subtypes, but phosphorylation by PKC can antagonize this interaction.…”