Determinants of gestational diabetes mellitus: A case control study in a district tertiary care hospital in south India

Bhat, Mamta; Sp, Sarma; Menon, Sangeetha; Singh, GK

doi:10.4103/0973-3930.62599

Cited by 48 publications

(32 citation statements)

References 17 publications

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“… 10 , 34 Family history of diabetes was concluded in several cross sectional and prospective studies as a highly significant risk for developing GDM. 35 , 36 Wang et al found that 54.9% of the incidence of GDM was significantly found among pregnant women with PCOS compared to 14.3% of those in the control group. 18 Therefore, recognizing such risk factors among pregnant women in Yemen is important and should be done by the medical staff in order to prevent the adverse effects of GDM.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and risk factors of gestational diabetes mellitus in Yemen

Ali

Mehrass

Al-Adhroey

et al. 2016

IJWH

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PurposeGestational diabetes mellitus (GDM) continues to be a significant health disorder triggering harmful complications in pregnant women and fetuses. Our knowledge of GDM epidemiology in Yemen is largely based on very limited data. The aim of this study was, therefore, to determine the prevalence and risk factors of GDM among pregnant women in Dhamar governorate, Yemen.Patients and methodsA total of 311 subjects were randomly selected for this cross sectional survey. Health history data and blood samples were collected using a pretested questionnaire. To determine the prevalence of GDM, the fasting and random blood glucose techniques were applied according to the recommendations of the American Diabetes Association, using alternative methods that are more convenient to the targeted population. Poisson’s regression model incorporating robust sandwich variance was utilized to assess the association of potential risk factors in developing GDM.ResultsThe prevalence of GDM was found to be 5.1% among the study population. Multivariate analysis confirmed age ≥30 years, previous GDM, family history of diabetes, and history of polycystic ovary syndrome as independent risk factors for GDM prevalence. However, body mass index ≥30 kg/m2 and previous macrosomic baby were found to be dependent risk factors.ConclusionThis study reports new epidemiological information about the prevalence and risk factors of GDM in Yemen. Introduction of proper maternal and neonatal medical care and health education are important in order to save the mother and the baby.

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Section: Discussionmentioning

confidence: 99%

Prevalence and risk factors of gestational diabetes mellitus in Yemen

Ali

Mehrass

Al-Adhroey

et al. 2016

IJWH

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“…Several studies have reported various risk factors associated with higher rates of GDM, mainly focused on traditional risk factors such as age, BMI etc. [ 12 ; 15 – 17 ; 21 – 24 ], but much remains to be understood particularly about socio-economic factors behind the high rates of GDM.…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for Hyperglycaemia in Pregnancy in Tamil Nadu, India

et al. 2016

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IntroductionHyperglycaemia in pregnancy (HIP), i.e. gestational diabetes mellitus (GDM) and diabetes in pregnancy (DIP), increases the risk of various short- and long-term adverse outcomes. However, much remains to be understood about the role of different risk factors in development of HIP.ObjectiveThe aims of this observational study were to examine the role of potential risk factors for HIP, and to investigate whether any single or accumulated risk factor(s) could be used to predict HIP among women attending GDM screening at three centres in urban, semi-urban and rural Tamil Nadu, India.MethodologyPregnant women underwent a 75 g oral glucose tolerance test. Data on potential risk factors was collected and analysed using logistical regression analysis. Receiver operating characteristic (ROC) curves, sensitivity, specificity and predictive values were calculated for significant risk factors and a risk factor scoring variable was constructed.ResultsHIP was prevalent in 18.9% of the study population (16.3% GDM; 2.6% DIP). Increasing age and BMI as well as having a mother only or both parents with diabetes were significant independent risk factors for HIP. Among women attending the rural health centre a doubling of income corresponded to an 80% increased risk of HIP (OR 1.80, 95%CI 1.10–2.93; p = 0.019), whereas it was not significantly associated with HIP among women attending the other health centres. The performance of the individual risk factors and the constructed scoring variable differed substantially between the three health centres, but none of them were good enough to discriminate between those with and without HIP.ConclusionsThe findings highlight the importance of socio-economic circumstances and intergenerational risk transmission in the occurrence of HIP as well as the need for universal screening.

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“…[ 13 14 15 ] In the setting of high prevalence of type 2 diabetes, these women also are prone to have a positive family history which also adds to the risk of gestational diabetes. [ 13 ] It is inevitable for the state's health system to be equipped to face the consequences of the burgeoning burden of gestational diabetes in the near future. Understanding the various outcomes of gestational diabetes would be the key to initiate the cascade of preparatory steps to tackle them.…”

Section: Introductionmentioning

confidence: 99%

Maternal and neonatal outcomes of gestational diabetes: A retrospective cohort study from Southern India

Sreelakshmi¹,

Nair

Soman

et al. 2015

J Family Med Prim Care

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Background:The prevalence of gestational diabetes is on the rise. Understanding the various outcomes of it is necessary to face this challenge.Objectives:To study the frequency of occurrence of various maternal and fetal outcomes among gestational diabetes patients.Methods:This is a retrospective cohort study conducted in rural Kerala, a southern state of India. The study participants were followed up for a period of 4 years, from 2007 to 2011. The participants included 60 women with gestational diabetes and 120 women without gestational diabetes. Gestational diabetes was the major exposure variable. The frequencies of various outcomes were computed. Multivariable logistic regression was done to compute the risk for various outcomes in gestational diabetes.Results:The major outcomes included termination of pregnancy by caesarean section, long-term progression to type 2 diabetes, in-born nursery (IBN) admissions and increased neonatal birth weight. The maximum adjusted RR [13.2 (1.5-116.03)] was for the development of type 2 DM later.Conclusion:Gestational diabetes can result in significant feto-maternal outcomes; so better facilities are needed to manage gestational diabetes.

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Determinants of gestational diabetes mellitus: A case control study in a district tertiary care hospital in south India

Cited by 48 publications

References 17 publications

Prevalence and risk factors of gestational diabetes mellitus in Yemen

Prevalence and risk factors of gestational diabetes mellitus in Yemen

Risk Factors for Hyperglycaemia in Pregnancy in Tamil Nadu, India

Maternal and neonatal outcomes of gestational diabetes: A retrospective cohort study from Southern India

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