Determinants of In-Hospital Death Among the Very Elderly with Acute Myocardial Infarction

Seguchi, Masaru; Sakakura, Kenichi; Tsukui, Takunori; Yamamoto, Kei; Taniguchi, Yousuke; Wada, Hiroshi; Momomura, Shin‐ichi; Fujita, Hideo

doi:10.1536/ihj.20-165

Cited by 14 publications

(23 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…19) Diabetes mellitus was defined as hemoglobin A1c "6.5% (national glycolhemoglobin standardization program (NGSP) value) or treatment for diabetes mellitus. 20,21) Dyslipidemia was defined as total cholesterol " 220 mg/dL, low-density lipoprotein cholesterol " 140 mg/dL, or treatment for dyslipidemia. 22) We used the laboratory data at admission.…”

Section: Methodsmentioning

confidence: 99%

Factors Associated with In-Hospital Death in Patients with Killip Class 3 Acute Myocardial Infarction

et al. 2021

Self Cite

View full text Add to dashboard Cite

The clinical outcomes in acute myocardial infarction (AMI) patients with Killip class 3 are often inconsistent with those in the literature, and the factors associated with poor outcomes have not been sufficiently investigated. The purpose of this study was to identify factors associated with in-hospital death in AMI patients with Killip class 3. We included 205 AMI patients with Killip class 3, and divided them into a survived group (n = 189) and in-hospital death group (n = 16). The primary objective was to identify factors associated with inhospital death using multivariate analysis. Age was significantly younger in the survived group than in the inhospital death group (73.1 ± 11.2 versus 83.2 ± 6.2 years, P < 0.001). Systolic blood pressure (SBP) was significantly higher in the survived group than in the in-hospital death group (150.0 ± 31.2 versus 124.8 ± 25.3 mmHg, P = 0.002). The prevalence of TIMI thrombus grade "2 was significantly greater in the in-hospital death group than in the survived group (56.3 versus 22.2%, P = 0.005). In multivariate logistic regression analysis, in-hospital death was significantly associated with age [odds ratio (OR) 1.168, 95% confidence interval (CI) 1.061-1.287, P = 0.002] and TIMI thrombus grade "2 (versus !1: OR 5.743, 95% CI 1.717-19.214, P = 0.005), and inversely associated with SBP on admission (per 10 mmHg increase: OR 0.764, 95% CI 0.613-0.953, P = 0.017). In conclusion, in-hospital death was associated with age and coronary thrombus burden, and was inversely associated with SBP on admission in patients with Killip class 3. It may be important to recognize these high risk features to improve the clinical outcomes of patients with Killip class 3.

show abstract

Section: Methodsmentioning

confidence: 99%

Factors Associated with In-Hospital Death in Patients with Killip Class 3 Acute Myocardial Infarction

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…Bradycardia was defined as a rate below 60 beats per minute [17]. Hypertension was defined as systolic blood pressure (SBP) >140 mmHg, diastolic blood pressure >90 mmHg, or medical treatment for hypertension [18,19]. Diabetes mellitus was defined as hemoglobin A1c (HbA1c) �6.5% or treatment for diabetes mellitus [19,20].…”

Section: Definitionsmentioning

confidence: 99%

“…Hypertension was defined as systolic blood pressure (SBP) >140 mmHg, diastolic blood pressure >90 mmHg, or medical treatment for hypertension [18,19]. Diabetes mellitus was defined as hemoglobin A1c (HbA1c) �6.5% or treatment for diabetes mellitus [19,20]. Dyslipidemia was defined as total cholesterol �220 mg/dL, low-density lipoprotein cholesterol �140 mg/dL, or treatment for dyslipidemia [19,20].…”

Section: Definitionsmentioning

confidence: 99%

“…Diabetes mellitus was defined as hemoglobin A1c (HbA1c) �6.5% or treatment for diabetes mellitus [19,20]. Dyslipidemia was defined as total cholesterol �220 mg/dL, low-density lipoprotein cholesterol �140 mg/dL, or treatment for dyslipidemia [19,20]. We also calculated estimated glomerular filtration rate (eGFR) using serum creatinine (Cr), age, weight, and gender according to the following formula: eGFR = 194×Cr −1.094 ×age −0.287 (male), or eGFR = 194×Cr −1.094 ×age −-0.287 ×0.739 (female) [21].…”

Section: Definitionsmentioning

confidence: 99%

“…We also calculated estimated glomerular filtration rate (eGFR) using serum creatinine (Cr), age, weight, and gender according to the following formula: eGFR = 194×Cr −1.094 ×age −0.287 (male), or eGFR = 194×Cr −1.094 ×age −-0.287 ×0.739 (female) [21]. Shock was defined as SBP <90 mmHg, vasopressors required to maintain blood pressure, or attempted cardiopulmonary resuscitation [19,20]. Left ventricular ejection fraction (LVEF) was measured using a modified Simpson method.…”

Section: Definitionsmentioning

confidence: 99%

See 2 more Smart Citations

Factors associated with temporary pacing insertion in patients with inferior ST-segment elevation myocardial infarction

et al. 2021

Self Cite

View full text Add to dashboard Cite

Background High-degree atrioventricular block (HAVB) is a prognostic factor for survival in patients with inferior ST-segment elevation myocardial infarction (STEMI). However, there is little information about factors associated with temporary pacing (TP). The aim of this study was to find factors associated with TP in patients with inferior STEMI. Methods We included 232 inferior STEMI patients, and divided those into the TP group (n = 46) and the non-TP group (n = 186). Factors associated with TP were retrospectively investigated using multivariate logistic regression model. Results The incidence of right ventricular (RV) infarction was significantly higher in the TP group (19.6%) than in the non-TP group (7.5%) (p = 0.024), but the incidence of in-hospital death was similar between the 2 groups (4.3% vs. 4.8%, p = 1.000). Long-term major adverse cardiovascular events (MACE), which were defined as a composite of all-cause death, non-fatal myocardial infarction (MI), target vessel revascularization (TVR) and readmission for heart failure, were not different between the 2 groups (p = 0.100). In the multivariate logistic regression analysis, statin at admission [odds ratio (OR) 0.230, 95% confidence interval (CI) 0.062–0.860, p = 0.029], HAVB at admission (OR 9.950, 95% CI 4.099–24.152, p<0.001), and TIMI-thrombus grade ≥3 (OR 10.762, 95% CI 1.385–83.635, p = 0.023) were significantly associated with TP. Conclusion Statin at admission, HAVB at admission, and TIMI-thrombus grade ≥3 were associated with TP in patients with inferior STEMI. Although the patients with TP had the higher incidence of RV infarction, the incidence of in-hospital death and long-term MACE was not different between patients with TP and those without.

show abstract

Comparison of Long-Term Clinical Outcomes of Elective Percutaneous Coronary Intervention Between Complex and High-risk Intervention in Indicated Patients (CHIP) versus Non-CHIP

Fujimoto

Sakakura

Jinnouchi

et al. 2023

The American Journal of Cardiology

View full text Add to dashboard Cite

Determinants of In-Hospital Death Among the Very Elderly with Acute Myocardial Infarction

Cited by 14 publications

References 35 publications

Factors Associated with In-Hospital Death in Patients with Killip Class 3 Acute Myocardial Infarction

Factors Associated with In-Hospital Death in Patients with Killip Class 3 Acute Myocardial Infarction

Factors associated with temporary pacing insertion in patients with inferior ST-segment elevation myocardial infarction

Comparison of Long-Term Clinical Outcomes of Elective Percutaneous Coronary Intervention Between Complex and High-risk Intervention in Indicated Patients (CHIP) versus Non-CHIP

Contact Info

Product

Resources

About