Determinants of Oocyte Quality: Impact on In Vitro Fertilization Failures

Combelles, Catherine M.H.; Rawe, Vanesa Y.

doi:10.1007/978-0-85729-826-3_21

Cited by 3 publications

(4 citation statements)

References 152 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The natural fertilization process of mammals happens according to certain precise processes with temporal characteristics, including the interaction between the spermatozoon and oocyte-cumulus complex, the acrosome reaction, travel of spermatozoa through the zona pellucida, the combination of the plasma membrane of spermatozoon-oocyte, the cortex reaction, and pronucleus formation (Combelles and Rawe, 2013). The traditional 18-hour co-incubation of gametes was originally established for practical reasons.…”

Section: Discussionmentioning

confidence: 99%

Differential effects of short co-incubation of gametes and early removal of cumulus cells in patients with different fertilizing capabilities

Zhou

Wang

Xing

et al. 2016

Reproductive BioMedicine Online

View full text Add to dashboard Cite

The objective of this retrospective study was to evaluate the embryological and clinical outcomes of short co-incubation of gametes and early removal of cumulus cells (SCGERCC) in patients with good IVF capability and those with complete fertilization failure treated by rescue intracytoplasmic sperm injection (ICSI). The study included 257 couples with >60% fertilization rate (SCGERCC group) in the SCGERCC cycle, 72 couples with complete fertilization failure in the SCGERCC cycle given early rescue ICSI treatment (early rescue group), and 219 couples who underwent IVF cycles with overnight co-incubation of gametes with >60% fertilization rate (traditional IVF group). The results showed that the SCGERCC group had a higher multi-pronuclei rate (13.34%, P < 0.001) than the early rescue ICSI (5.15%) and traditional IVF (6.15%) groups. The good quality embryo rate was higher in the SCGERCC group, but implantation, clinical pregnancy and live-birth rates (37.21%, 36.92% and 38.20% for SCGERCC, early rescue and traditional IVF groups, respectively) were comparable in all three groups. The study indicated that SCGERCC followed by rescue ICSI helped couples with initial complete fertilization failure attain clinical outcomes comparable with the other two groups, but it significantly increased the multi-pronuclei rate in couples with good fertilizing capabilities.

show abstract

Section: Discussionmentioning

confidence: 99%

Differential effects of short co-incubation of gametes and early removal of cumulus cells in patients with different fertilizing capabilities

Zhou

Wang

Xing

et al. 2016

Reproductive BioMedicine Online

View full text Add to dashboard Cite

show abstract

“…Concerns over the long-term effects of repeated COH have been raised with respect to increased cancer risks and premature follicle depletion, but the practice continues. 284 Studies of this kind suggest that altering the pace of follicle development with exogenous gonadotropins does not exert long-term effects on developmental competence unless additional challenges are imposed on embryos by maintaining them in culture. 283 In one study using mice subjected to four rounds of stimulation, a progressive decrease in oocyte ATP levels was noted in relation to the number of rounds of stimulation.…”

Section: Controlled Ovarian Hyperstimulation-more Oocytes But Are Thementioning

confidence: 99%

The Mammalian Oocyte

Albertini

2015

Knobil and Neill's Physiology of Reproduction

View full text Add to dashboard Cite

“…Whether de novo actin polymerization is initiated around the sperm nucleus or pre-existing F-actin in the female cytoplasm adheres to the sperm nucleus needs to be determined. (Combelles & Rawe, 2013;Gibeaux & Knop, 2013;Loppin, Dubruille, & Horard, 2015;Poccia & Collas, 1996). In Ascaris and most mammals, pronuclei remain separate until the initiation of the first zygotic mitosis.…”

Section: Gamete Nuclear Migrationmentioning

confidence: 99%

“…Like in yeast ( Saccharomyces cerevisiae ) karyogamy, gametes of sea urchins and sea stars undergo fusion of pronuclear envelopes, composed of two lipid bilayers, the outer and inner nuclear membranes. Ascaris , mammals, and most arthropods including insects, on the contrary, exhibit different modes of parental genome fusion (Combelles & Rawe, 2013; Gibeaux & Knop, 2013; Loppin, Dubruille, & Horard, 2015; Poccia & Collas, 1996). In Ascaris and most mammals, pronuclei remain separate until the initiation of the first zygotic mitosis.…”

Section: Karyogamymentioning

confidence: 99%

Cellular dynamics of double fertilization and early embryogenesis in flowering plants

et al. 2020

View full text Add to dashboard Cite

Flowering plants (angiosperms) perform a unique double fertilization in which two sperm cells fuse with two female gamete cells in the embryo sac to develop a seed. Furthermore, during land plant evolution, the mode of sexual reproduction has been modified dramatically from motile sperm in the early-diverging land plants, such as mosses and ferns as well as some gymnosperms (Ginkgo and cycads) to non-motile sperm that are delivered to female gametes by the pollen tube in flowering plants. Recent studies have revealed the cellular dynamics and molecular mechanisms for the complex series of double fertilization processes and elucidated differences and similarities between animals and plants. Here, together with a brief comparison with animals, we review the current understanding of flowering plant zygote dynamics, covering from gamete nuclear migration, karyogamy and polyspermy block, to zygotic genome activation as well as asymmetrical division of the zygote. Further analyses of the detailed molecular and cellular mechanisms of flowering plant fertilization should shed light on the evolution of the unique sexual reproduction of flowering plants.

show abstract

Determinants of Oocyte Quality: Impact on In Vitro Fertilization Failures

Cited by 3 publications

References 152 publications

Differential effects of short co-incubation of gametes and early removal of cumulus cells in patients with different fertilizing capabilities

Differential effects of short co-incubation of gametes and early removal of cumulus cells in patients with different fertilizing capabilities

The Mammalian Oocyte

Cellular dynamics of double fertilization and early embryogenesis in flowering plants

Contact Info

Product

Resources

About