Determinants of patient compliance in allergic rhinoconjunctivitis

Abstract

The variation in the methodologies used and the durations of treatments assessed in current compliance research in the field of allergic rhinoconjunctivitis decreases the comparability of results. Therefore, a clear definition of compliance measured in clinical trials with allergic rhinoconjunctivitis sufferers is needed. Moreover, a gold standard for measuring and reporting compliance should be determined to enable better interstudy comparability of the rates and determinants of compliance.

Comprehensive Study of Patients’ Compliance with Sublingual Immunotherapy in House Dust Mite Perennial Allergic Rhinitis

“…data are in agreement with several previously published studies of patients with PAR, which have reported the rates of around 70-80%[10,15,[17][18][19][20][21][22]. Another study has reported a higher compliance of approximately 97%[20].However, in that study, the patients counted the pills themselves and reported via a Variations caused by the method of compliance measurement were apparent in our study.…”

“…The available data on the patient adherence to allergen-specific immunotherapy are often conflicting [11,12]. In particular, in allergic rhinitis, compliance rates for sublingual administration range between 70% and 97% [10,[13][14][15][16][17][18][19][20][21][22]. This wide variation might be explained by differences in the characteristics and methodology of the studies, such as the population profiles and the definition of compliance [23].…”

“…Young patients might not have different comorbidities but face different challenges to compliance. A lack of compliance is a common multifactorial problem, which arises not only from treatment-related factors but also due to the condition itself and the societal and health-care system factors [10]. The available data on the patient adherence to allergen-specific immunotherapy are often conflicting [11,12].…”

“…The model gives a predictive value of 35.5% for noncompliant patients and 94.7% for compliant patients c According to the ARIA classification[22] d According to the Valero et al work[23] integrate the SLIT treatment into their daily routines. Adequate information on managing the most common local reactions in the mouth or gastrointestinal tract[10,36] might also be of value.Two interesting findings are worth emphasizing. First, the cost of treatment only took the fourth place in the ranking by noncompliant adult patients.…”

Characteristics and predictors of allergic rhinitis undertreatment in primary care

“…It is known that lack of efficacy, side effects, treatment duration, and costs are associated with a lower compliance to allergic rhinitis treatment. 18 In a recent Spanish survey, just 15% of allergic rhinitis patients sensitized to dust mites reported an improvement after pharmacological treatment. 19 Another possibility would be that patients with perennial allergic rhinitis do not take adequate treatment due to an effective allergen avoidance.…”