Determinants of Peripheral Muscle Strength and Activity in Daily Life in People With Bronchiectasis

Camargo, Anderson Alves de; Boldorini, Jacqueline Cristina; Holland, Anne E; Castro, Rejane Agnelo Silva de; Lanza, Fernanda Moura; Athanazio, Rodrigo Abensur; Rached, Samia Zahi; Carvalho-Pinto, Regina Maria; Cukier, Alberto; Stelmach, Rafaël; Corso, Simone Dal

doi:10.1093/ptj/pzx123

Cited by 29 publications

(29 citation statements)

References 33 publications

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“…Compared with healthy controls, bronchiectasis patients have a significantly reduced exercise capacity. [17][18][19] One of the limiting factors of physical activity is the perception of dyspnea, as evaluated by the Medical Research Council (MRC) dyspnea score. 19 MRC dyspnea score was evidently higher in patients with bronchiectasis when compared with healthy controls.…”

Section: Exercise Capacitymentioning

confidence: 99%

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The Deteriorating Patient: Therapies Including Lung Transplantation

Detailleur¹,

Vos²,

Goeminne

2021

Semin Respir Crit Care Med

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In this review paper, we discuss the characteristics that define severe bronchiectasis and which may lead to deterioration of noncystic fibrosis bronchiectasis. These characteristics were used to establish the current severity scores: bronchiectasis severity index (BSI), FACED, and E-FACED (exacerbation frequency, forced expiratory volume in 1 second, age, colonization, extension and dyspnea score). They can be used to predict mortality, exacerbation rate, hospital admission, and quality of life. Furthermore, there are different treatable traits that contribute to severe bronchiectasis and clinical deterioration. When present, they can be a target of the treatment to stabilize bronchiectasis.One of the first steps in treatment management of bronchiectasis is evaluation of compliance to already prescribed therapy. Several factors can contribute to treatment adherence, but to date no real interventions have been published to ameliorate this phenomenon. In the second step, treatment in deteriorating patients with bronchiectasis should be guided by the predominant symptoms, for example, cough, sputum, difficulty expectoration, exacerbation rate, or physical impairment. In the third step, we evaluate treatable traits that could influence disease severity in the deteriorating patient. Finally, in patients who are difficult to treat despite maximum medical treatment, eligibility for surgery (when disease is localized), should be considered. In case of end-stage disease, the evaluation for lung transplantation should be performed. Noninvasive ventilation can serve as a bridge to lung transplantation in patients with respiratory failure.

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Section: Exercise Capacitymentioning

confidence: 99%

“…Another factor that is significantly related to reduced exercise capacity is peripheral muscle strength and peripheral muscle endurance. 18,19 These extrapulmonary features can be addressed when providing pulmonary rehabilitation programs.…”

Section: Exercise Capacitymentioning

confidence: 99%

The Deteriorating Patient: Therapies Including Lung Transplantation

Detailleur¹,

Vos²,

Goeminne

2021

Semin Respir Crit Care Med

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“…Many patients with bronchiectasis have marked impairments in physical function and physical activity. Compared to age‐matched healthy controls, patients with bronchiectasis have an average reduction in exercise capacity of 33%, as well as a 25% reduction in quadriceps strength and 26% reduction in the number of steps taken each day . Lower exercise capacity and physical activity levels are both associated with worse dyspnoea .…”

Section: Pulmonary Rehabilitation In Specific Patient Groupsmentioning

confidence: 99%

“…Compared to age‐matched healthy controls, patients with bronchiectasis have an average reduction in exercise capacity of 33%, as well as a 25% reduction in quadriceps strength and 26% reduction in the number of steps taken each day . Lower exercise capacity and physical activity levels are both associated with worse dyspnoea . This is clinically important because dyspnoea is a strong predictor of mortality in bronchiectasis .…”

Section: Pulmonary Rehabilitation In Specific Patient Groupsmentioning

confidence: 99%

Practical approach to establishing pulmonary rehabilitation for people with non‐COPD diagnoses

2019

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Pulmonary rehabilitation is a core aspect in the management of patients with chronic respiratory diseases. This paper describes a practical approach to establishing pulmonary rehabilitation for patients with non-COPD diagnoses using examples from the interstitial lung disease (ILD), pulmonary hypertension (PH), bronchiectasis and lung cancer patient populations. Aspects of pulmonary rehabilitation, including the rationale, patient selection, setting of programmes, patient assessment and training components (both exercise and non-exercise aspects), are discussed for these patient groups. Whilst there are many similarities in the rationale and application of pulmonary rehabilitation across these non-COPD populations, there are also many subtle differences, which are discussed in detail in this paper. With consideration of these factors, pulmonary rehabilitation programmes can be adapted to facilitate the inclusion of respiratory patients with non-COPD diagnoses.

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“…[40] In severe asthma and bronchiectasis, muscle strength is considerably less studied. There is a trend towards decreased quadriceps muscle strength in bronchiectasis, [41,42] but little data exist reporting an association between strength and HRQoL. [41] In moderate-severe asthma, impairment of quadriceps endurance, but not strength, was observed in adults [43] and children.…”

Section: Mmentioning

confidence: 99%