“…The number of patients in both of these studies was low (30 and 22 patients, respectively) and they used different criteria to detect late potentials. Only one of the 30 patients in the non-ischemic cardiomyopathy group of Meinhertz et al 7 had an altered signal averaged electrocardiogram. Eleven patients died during the course of the study of which 5 were a result of heart failure evolution.…”
Section: Discussionmentioning
confidence: 93%
“…Nevertheless there is controversy. The studies of Meinertz et al 7 and Middlekauff et al 8 did not find the signal averaged electrocardiogram to be predictive of sudden death or ventricular arrhythmia. The number of patients in both of these studies was low (30 and 22 patients, respectively) and they used different criteria to detect late potentials.…”
Section: Discussionmentioning
confidence: 93%
“…In heart failure patients, the presence of late potentials has been investigated in small case studies that do not include patients with Chagas disease [6][7][8] .…”
“…The number of patients in both of these studies was low (30 and 22 patients, respectively) and they used different criteria to detect late potentials. Only one of the 30 patients in the non-ischemic cardiomyopathy group of Meinhertz et al 7 had an altered signal averaged electrocardiogram. Eleven patients died during the course of the study of which 5 were a result of heart failure evolution.…”
Section: Discussionmentioning
confidence: 93%
“…Nevertheless there is controversy. The studies of Meinertz et al 7 and Middlekauff et al 8 did not find the signal averaged electrocardiogram to be predictive of sudden death or ventricular arrhythmia. The number of patients in both of these studies was low (30 and 22 patients, respectively) and they used different criteria to detect late potentials.…”
Section: Discussionmentioning
confidence: 93%
“…In heart failure patients, the presence of late potentials has been investigated in small case studies that do not include patients with Chagas disease [6][7][8] .…”
“…Results obtained by analysing the signal-averaged recording in the frequencydomain have been comparable: nine out of 10 patients with sustained ventricular tachycardia had late potentials, vs only four out of 21 patients without sustained ventricular tachycardia' 19 '. However, there are controversies concerning the incidence of ventricular late potentials in non-ischaemic dilated cardiomyopathy' 9 ', and a recent study failed to show any correlation between the presence of late potentials and sudden death in patients with advanced heart failure 1 ' 81 . The presence of ventricular late potentials does not seem to be helpful in identifying patients with inducible ventricular tachyarrhythmias in electrophysiological study 1 ' 6 -20 '.…”
“…In patients with NSVT, the presence of late potentials varies and does not seem to predict the occurrence of sudden death 143 . Mancini et al 144 evaluated the prognostic value of the signal averaged ECG (SAE) in patients with nonis-chemic dilated cardiomyopathy.…”
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